Sutton Jonathan M
Northwestern University, Department of Psychology, 2029 Sheridan Road, Swift Hall 102, Evanston, IL 60208, USA.
Clin Psychol Rev. 2007 Jun;27(5):552-71. doi: 10.1016/j.cpr.2007.01.014. Epub 2007 Feb 7.
Since 1990, significant efforts have been made towards developing interventions to prevent depression in youth. Meta-analyses of preventive interventions have consistently yielded small but significant effect sizes in the short-term prevention of depression. However, the maintenance of intervention effects over extended follow-ups ranging from 6 months to 3 years has not been consistently demonstrated. In this qualitative review, significant methodological issues that continue to be of concern are discussed. Illustrative studies are described to highlight the accomplishments and limitations of interventions to date. Particular areas in need of attention include the implementation of booster sessions, use of appropriate statistical analyses, examination of multiple outcome variables, augmentation of protective factors, and exploration of mediators and moderators of intervention effects. Future directions for the field of depression prevention are outlined.
自1990年以来，人们为开发预防青少年抑郁症的干预措施付出了巨大努力。预防性干预措施的荟萃分析在抑郁症的短期预防中始终产生虽小但显著的效应量。然而，干预效果在长达6个月至3年的延长随访期内的维持情况尚未得到一致证明。在这篇定性综述中，讨论了一些仍令人担忧的重大方法学问题。描述了一些具有代表性的研究，以突出迄今为止干预措施的成就和局限性。需要特别关注的领域包括强化课程的实施、适当统计分析的使用、多个结果变量的检验、保护因素的增强以及干预效果的中介和调节因素的探索。概述了抑郁症预防领域的未来方向。
