Si Jin-Ping, Huang Wen-Hua, Guo Bao-Lin, Ruan Xiu-Chun, Li Shi-Jie
Zhejiang Forestry College, lin'an 311300, China.
Zhongguo Zhong Yao Za Zhi. 2006 Dec;31(24):2026-30.
To study the content variation of triptolide in medicinal material of Tripterygium and provide theoretical basis for the hereditary improvement, the gathering and process, the quality evaluation and the provenance division in medicinal material of Tripterygium.
HPLC method was used to determine the content of triptolide.
The relations between triptolide and germplasm, growth year, gathering season were found out basically.
The triptolide contents in xylem are affected by hereditary factors remarkably. While the triptolide contents in phloem are not affected obviously. The accumulation of triptolide needs the certain growth years. However when growth is beyond certain years, the triptolide content decreases with the disintegration of secondary metabolism in xylem. The triptolide in xylem is highest in winter and decreasing in growing season. The triptolide in phloem is less affected by the season.
研究雷公藤药材中雷公藤甲素的含量变化，为雷公藤药材的遗传改良、采收加工、质量评价及产地划分提供理论依据。
采用高效液相色谱法测定雷公藤甲素的含量。
基本摸清了雷公藤甲素与种质、生长年限、采收季节之间的关系。
木质部中雷公藤甲素含量受遗传因素影响显著，韧皮部中雷公藤甲素含量受影响不明显。雷公藤甲素的积累需要一定的生长年限，但生长超过一定年限后，木质部中次生代谢产物分解，雷公藤甲素含量降低。木质部中雷公藤甲素在冬季含量最高，生长季节降低，韧皮部中雷公藤甲素受季节影响较小。
