Deng Ying-Xian, Ma Zeng-Chun, Tan Hong-Ling, Xiao Cheng-Rong, Wang Yu-Guang, Gao Yue
The General Hospital, the Air Force of the Chinese People's Liberation Army, Beijing 100036, China.
Zhongguo Zhong Yao Za Zhi. 2006 Dec;31(24):2070-3.
To explore the cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy.
Rats were ovariectomized and administered drugs for 3 monthes. Bone mineral density and biomechanics properties, histomorphometric analysis and biochemical index such as calcium, phosphorus, alkaline phosphatase were detected.
Jiangu Fufang could significantly increase bone density and biomechanics properties. The level of calcium, phosphorus and alkaline phosphatase were restored by Jiangu Fufang. Jiangu Fufang could significantly increase area of bone trabecula, thickness of cortical bone and bone trabecula.
Jiangu Fufang could cure osteoporosis through increasing bone mineral density, improving bone biomechanics properties, and effecting bone metabolism.
探讨健骨复方对去卵巢所致骨质疏松模型的治疗作用。
将大鼠去卵巢并给药3个月。检测骨密度、生物力学性能、组织形态计量学分析以及钙、磷、碱性磷酸酶等生化指标。
健骨复方可显著提高骨密度和生物力学性能。健骨复方使钙、磷和碱性磷酸酶水平恢复正常。健骨复方可显著增加骨小梁面积、皮质骨厚度和骨小梁厚度。
健骨复方可通过增加骨密度、改善骨生物力学性能及影响骨代谢来治疗骨质疏松症。
