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急性创伤性主动脉瘤:杜克大学1970年至1990年的经验

Acute traumatic aortic aneurysm: the Duke experience from 1970 to 1990.

作者信息

Duhaylongsod F G, Glower D D, Wolfe W G

机构信息

Department of Surgery, Duke University Medical Center, Durham, NC 27710.

出版信息

J Vasc Surg. 1992 Feb;15(2):331-42; discussion 342-3. doi: 10.1067/mva.1992.34439.

Abstract

Improvements in the operative management of acute traumatic thoracic aortic aneurysm have resulted in safe and expeditious repair. Nonetheless, multisystem injuries continue to inflict significant numbers of deaths. From 1970 to 1990, 108 patients with acute traumatic thoracic aortic aneurysm were evaluated. Mean injury severity score, excluding aortic injury, was 17.5. Ninety-three patients (86%) survived beyond initial resuscitation and came to operation. Median interval from injury to aortic repair was 8 hours (range, 2 hours to 19 days); there were five operative deaths. Lethal nonaortic injuries included 18 closed head injuries, four myocardial contusions, two intraabdominal vascular injuries, and one pulmonary contusion. The overall mortality rate was 39% of total admissions (42 of 108), and 29% of survivors of resuscitation (27 of 93). It is significant that only 11 of the 42 deaths (26%) were directly attributable to thoracic aortic aneurysm. Adjuncts to prevent spinal cord ischemia (shunt/bypass) were used in 76 patients, whereas 12 underwent clamp/repair. Postoperative paraplegia developed in 5 of 79 patients (6.8%, including 4 of 68 (5.9%) repaired with shunt/bypass and 1 of 11 (9.1%) repaired with clamp/repair (p = NS). Among those who developed paraplegia, the injury severity score was 27.0, and the median interval from injury to repair was 4.9 hours (range, 2 to 6.5). Intraoperative hypotension occurred in three of five patients with paraplegia. Death in patients with thoracic aortic aneurysm is due primarily to associated injuries and has remained relatively constant over the 20-year period of review. Overall injury severity, intraoperative hypotension, and extensive aortic tissue destruction may correlate with the development of postoperative paraplegia; however, a larger population sample is required to confirm this conclusion. A plea is made for standardized reporting of all patients with thoracic aortic aneurysm.

摘要

急性创伤性胸主动脉瘤手术管理的改进已实现安全、快速修复。尽管如此,多系统损伤仍导致大量死亡。1970年至1990年期间,对108例急性创伤性胸主动脉瘤患者进行了评估。排除主动脉损伤后的平均损伤严重程度评分为17.5。93例患者(86%)在初始复苏后存活并接受手术。从受伤到主动脉修复的中位间隔时间为8小时(范围为2小时至19天);有5例手术死亡。致命的非主动脉损伤包括18例闭合性颅脑损伤、4例心肌挫伤、2例腹内血管损伤和1例肺挫伤。总死亡率为总入院人数的39%(108例中的42例),复苏幸存者的死亡率为29%(93例中的27例)。值得注意的是,42例死亡中只有11例(26%)直接归因于胸主动脉瘤。76例患者使用了预防脊髓缺血的辅助措施(分流/旁路),而12例接受了夹闭/修复。79例患者中有5例发生术后截瘫(6.8%,包括68例分流/旁路修复患者中的4例(5.9%)和11例夹闭/修复患者中的1例(9.1%),p=无显著性差异)。在发生截瘫的患者中,损伤严重程度评分为27.0,从受伤到修复的中位间隔时间为4.9小时(范围为2至6.5小时)。5例截瘫患者中有3例术中出现低血压。胸主动脉瘤患者的死亡主要归因于相关损伤,在20年的回顾期内相对稳定。总体损伤严重程度、术中低血压和广泛的主动脉组织破坏可能与术后截瘫的发生有关;然而,需要更大的人群样本才能证实这一结论。呼吁对所有胸主动脉瘤患者进行标准化报告。

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