Westerberg H, Jacobaeus H, Hirvikoski T, Clevberger P, Ostensson M-L, Bartfai A, Klingberg T
Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm.
Brain Inj. 2007 Jan;21(1):21-9. doi: 10.1080/02699050601148726.
To examine the effects of working memory (WM) training in adult patients with stroke.
A randomized pilot study with a treatment group and a passive control group; 18 participants (12 males) in a vocational age group (mean age 54 years) were randomized to either the treatment or the control condition. The intervention consisted of computerized training on various WM tasks for five weeks. A neuropsychological test battery and self-rating on cognitive functioning in daily life (the CFQ) were administered both before and after the treatment.
Statistically significant training effects were found on the non-trained tests for WM and attention, i.e., tests that measure related cognitive functions but are not identical to tasks in the training programme (Span board p < 0.05; PASAT p < 0.001; Ruff 2&7 p < 0.005). There was a significant decrease in symptoms of cognitive problems as measured by the CFQ (p < 0.005).
More than one year after a stroke, systematic WM training can significantly improve WM and attention.
研究工作记忆（WM）训练对成年中风患者的影响。
一项随机试点研究，设有治疗组和被动对照组；18名职业年龄组的参与者（12名男性）（平均年龄54岁）被随机分配到治疗组或对照组。干预措施包括针对各种WM任务进行为期五周的计算机化训练。在治疗前后均进行了神经心理测试组和日常生活认知功能自评（CFQ）。
在未训练的WM和注意力测试中发现了具有统计学意义的训练效果，即测量相关认知功能但与训练计划中的任务不同的测试（跨度板测试p<0.05；连续加法运算测试p<0.001；拉夫2和7测试p<0.005）。CFQ测量的认知问题症状有显著下降（p<0.005）。
中风一年多后，系统的WM训练可显著改善WM和注意力。
