Erasmus MC, Rotterdam, The Netherlands.
Neurorehabil Neural Repair. 2013 Feb;27(2):110-7. doi: 10.1177/1545968312455222. Epub 2012 Aug 15.
Stroke patients with a low memory self-efficacy (MSE) report more memory complaints than patients with a high MSE.
The aim of this study was to examine the effect of a memory-training program on MSE in the chronic phase after stroke and to identify which patients benefit most from the MSE training program.
In a randomized controlled trial, the effectiveness of the MSE training program (experimental group) was compared with a peer support program (control group) in chronic stroke patients. The primary outcome was MSE, measured using the Metamemory-In-Adulthood Questionnaire. Secondary outcomes included depression, quality of life, and objective verbal memory capacity. Changes in outcomes over the intervention period were compared between both groups. Demographic and clinical variables were studied as potential predictors of MSE outcome in the experimental group.
In total, 153 patients were included: mean age = 58 years (standard deviation [SD] = 9.7), 54.9% male, and mean of 54 months (SD = 37) after stroke. Of these, 77 were assigned to the training and 76 to the control group. Improvement of MSE (B = 0.40; P = .019) was significantly greater in the training than in the control group. No significant differences were found for the secondary outcomes. An increase in MSE after training was predicted by a younger age (B = -0.033; P = .006) and a better memory capacity (B = 0.043; P = .009), adjusted for baseline MSE.
MSE can be improved by the MSE training program for stroke patients. Younger patients and patients with a better memory capacity benefit most from the MSE training program (Dutch Trial Register: NTR-TC 1656).
记忆自我效能感（MSE）较低的中风患者比 MSE 较高的患者报告更多的记忆问题。
本研究旨在检验记忆训练方案对中风后慢性期 MSE 的影响，并确定哪些患者最受益于 MSE 训练方案。
在一项随机对照试验中，将 MSE 训练方案（实验组）与同伴支持方案（对照组）在慢性中风患者中进行比较。主要结局是使用成人元记忆问卷（Metamemory-In-Adulthood Questionnaire）测量的 MSE。次要结局包括抑郁、生活质量和客观言语记忆能力。比较两组干预期间结局的变化。研究了实验组中 MSE 结果的潜在预测因素，包括人口统计学和临床变量。
共纳入 153 例患者：平均年龄为 58 岁（标准差 [SD] = 9.7），54.9%为男性，中风后平均时间为 54 个月（SD = 37）。其中 77 例被分配到训练组，76 例被分配到对照组。与对照组相比，训练组 MSE 的改善（B = 0.40；P =.019）显著更大。次要结局没有发现显著差异。训练后 MSE 的增加可以通过年龄较小（B = -0.033；P =.006）和记忆能力较好（B = 0.043；P =.009）来预测，调整基线 MSE 后。
MSE 可以通过 MSE 训练方案来改善中风患者的 MSE。年轻患者和记忆能力较好的患者最受益于 MSE 训练方案（荷兰试验注册处：NTR-TC 1656）。
