Kraman Steve
University of Kentucky College of Medicine, Lexington, KY 40536, USA.
COPD. 2007 Mar;4(1):49-54. doi: 10.1080/15412550601169539.
The measurements of lung compliance, airway resistance and respiratory dead space as clinical tests have gradually fallen into disuse as the standard pulmonary function testing procedures; spirometry, lung volume and diffusing capacity measurement, followed, if necessary, by imaging have become the norm for diagnosis of COPD and other lung diseases. To have a real understanding of what spirometry and lung volume tests measure requires some knowledge of compliance and airway resistance. The respiratory dead space is an important global indicator of ventilation/perfusion relationships that remains of interest in the early detection of pulmonary emboli. There are other situations as well where it is clinically useful to perform the measurements described here, so these techniques, although generally set aside from the commonly used tests, should not be forgotten.
作为临床检测手段,肺顺应性、气道阻力和呼吸死腔的测量已逐渐不再作为标准肺功能检测程序使用;肺活量测定、肺容积和弥散能力测量,必要时辅以影像学检查,已成为慢性阻塞性肺疾病(COPD)和其他肺部疾病诊断的规范。要真正理解肺活量测定和肺容积测试所测量的内容,需要一些关于顺应性和气道阻力的知识。呼吸死腔是通气/灌注关系的一个重要整体指标,在肺栓塞的早期检测中仍具有重要意义。还有其他一些情况,在此进行所述测量在临床上也是有用的,所以这些技术虽然通常不被纳入常用检测方法,但不应被遗忘。