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澳大利亚维多利亚州社区药剂师的丁丙诺啡供应情况:认知、经验及发现的关键问题

Buprenorphine supply by community pharmacists in Victoria, Australia: perceptions, experiences and key issues identified.

作者信息

Nielsen Suzanne, Dietze Paul, Dunlop Adrian, Muhleisen Peter, Lee Nicole, Taylor David

机构信息

Turning Point Alcohol and Drug Centre, Fitzroy, Victoria, Australia.

出版信息

Drug Alcohol Rev. 2007 Mar;26(2):143-51. doi: 10.1080/09595230601146645.

Abstract

Buprenorphine is dispensed primarily in community pharmacies in Victoria, with buprenorphine prescribing expanding nationally. The aim of this paper was to examine issues that affect the delivery of buprenorphine in the community setting. A cross-sectional survey was conducted of 282 pharmacies participating in the methadone and buprenorphine programme across Victoria. Dispensing pharmacists completed the survey, designed to canvass issues around buprenorphine diversion and other issues related to the programme. Themes from the results indicated that there was concern from the majority of pharmacies with the issue of the supervision of buprenorphine and diversion of dispensed doses. The rate of suspected diversion was 1.5 times per 100 doses per month or 33 times per 100 clients per month. Seventy-four per cent of pharmacists indicated that this was a negative aspect of buprenorphine treatment. Frequency of suspected and confirmed diversion was associated with the number of pharmacy clients. Pharmacists' perceptions of issues related to buprenorphine appeared to affect opinions of buprenorphine clients and the buprenorphine programme more generally. Pharmacists believe that a significant level of diversion is occurring. This finding warrants serious attention, particularly in light of the increasing use of buprenorphine nationally and internationally.

摘要

丁丙诺啡主要在维多利亚州的社区药房配药,且丁丙诺啡的处方在全国范围内不断增加。本文旨在探讨影响社区环境中丁丙诺啡供应的问题。对维多利亚州参与美沙酮和丁丙诺啡项目的282家药房进行了横断面调查。配药药剂师完成了该调查,旨在探讨丁丙诺啡转移及与该项目相关的其他问题。结果主题表明,大多数药房对丁丙诺啡的监管问题和配药剂量的转移表示担忧。疑似转移率为每月每100剂1.5次或每月每100名客户33次。74%的药剂师表示这是丁丙诺啡治疗的一个负面因素。疑似和确认转移的频率与药房客户数量有关。药剂师对丁丙诺啡相关问题的看法似乎更普遍地影响了对丁丙诺啡客户和丁丙诺啡项目的看法。药剂师认为正在发生大量的转移。这一发现值得认真关注,尤其是鉴于丁丙诺啡在国内和国际上的使用不断增加。

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