Semba Richard D, Ricketts Erin P, Mehta Shruti F, Kirk Gregory D, Latkin Carl, Galai Noya, Vlahov David
Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
Am J Drug Alcohol Abuse. 2007;33(1):71-80. doi: 10.1080/00952990601082696.
Adherence and retention of female injection drug users (IDUs) in clinical trials are not well known and were evaluated among 458 female IDUs in a clinical trial in Baltimore. Of all, 62.9% were adherent to visits (attended > or = 80% of visits). Of women with > or = 1 visit after enrollment, 76% were adherent to treatment (took > or = 80% of pills); 27.7% were lost to follow-up (missed > or = 3 consecutive visits). Women nonadherent to visits were younger and less likely to be on methadone. Women lost to follow-up were younger, more often white, not on methadone, and injecting drugs daily. Fair-moderate adherence to visits and treatment occurs among female IDUs in a clinical trial.
女性注射吸毒者在临床试验中的依从性和留存率尚不清楚，在巴尔的摩的一项针对458名女性注射吸毒者的临床试验中对其进行了评估。总体而言，62.9%的人坚持就诊（就诊次数达到或超过80%）。在入组后有一次及以上就诊的女性中，76%坚持治疗（服药量达到或超过80%）；27.7%失访（连续错过3次及以上就诊）。不坚持就诊的女性更年轻，服用美沙酮的可能性更低。失访的女性更年轻，多为白人，未服用美沙酮，且每天注射毒品。在一项临床试验中，女性注射吸毒者对就诊和治疗的依从性为中等偏下。
