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利用细菌学实验室减少全科医生的抗生素处方。

Use of the bacteriology laboratory to decrease general practitioners' antibiotic prescribing.

作者信息

Gould Ian Malcolm, Mackenzie Fiona Marjorie, Shepherd Lorraine

机构信息

Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK.

出版信息

Eur J Gen Pract. 2007;13(1):13-5. doi: 10.1080/13814780601050764.

Abstract

OBJECTIVE

Use of the bacteriology laboratory to guide antibiotic prescribing in primary care is often considered inappropriate due to difficulties of access in a relevant time scale. The overnight analysis offered to general practitioners in the Grampian area of Scotland for the past 6 years (ABLE), and which had previously been shown to reduce antibiotic prescribing by two-thirds in a randomized controlled trial, was audited to see if it was being used correctly in general practice, that is to reduce unnecessary antibiotic prescribing.

METHODS

699 consultations were audited. Of these, 357 were ABLE patients. The other 342 were chosen because an antibiotic had been prescribed.

RESULTS

Only 36.7% (140) of the ABLE patients were prescribed an antibiotic, 65.7% being given a delayed action script. All but 10 were culture positive. ABLE patients had a greater proportion of urinary tract infections than the non-ABLE patients, but less lower-respiratory and skin or soft-tissue infection. The antibiotics prescribed reflected the differences in infection type. The repeat visit rate and repeat antibiotic prescription rate were almost identical between the two groups.

CONCLUSION

While the overall use of ABLE in Grampian is low, its use seems to be appropriate in that it is successfully being used to identify bacterial infection and reduce unnecessary antibiotic prescribing.

摘要

目的

由于在合理时间范围内获取结果存在困难,利用细菌学实验室指导初级医疗中的抗生素处方通常被认为是不合适的。对过去6年向苏格兰格兰扁地区的全科医生提供的过夜分析服务(ABLE)进行了审核,该服务在之前的一项随机对照试验中已被证明可将抗生素处方减少三分之二,审核目的是查看其在全科医疗中是否得到正确使用,即减少不必要的抗生素处方。

方法

对699次会诊进行了审核。其中,357例是ABLE患者。另外342例是因为已开具抗生素而被选中。

结果

只有36.7%(140例)的ABLE患者开具了抗生素,65.7%的患者拿到了延迟生效的处方。除10例之外,所有患者培养结果均为阳性。ABLE患者中尿路感染的比例高于非ABLE患者,但下呼吸道感染以及皮肤或软组织感染的比例较低。所开具的抗生素反映了感染类型的差异。两组的复诊率和重复抗生素处方率几乎相同。

结论

虽然ABLE在格兰扁地区的总体使用率较低,但它的使用似乎是恰当的,因为它成功地用于识别细菌感染并减少不必要的抗生素处方。

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