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用于(192)铱高剂量率和脉冲剂量率源远程剂量测定审核的热释光剂量计邮寄系统的开发。

Development of a TLD mailed system for remote dosimetry audit for (192)Ir HDR and PDR sources.

作者信息

Roué Amélie, Venselaar Jack L M, Ferreira Ivaldo H, Bridier André, Van Dam Jan

机构信息

EQUAL-ESTRO Laboratory, Villejuif, France.

出版信息

Radiother Oncol. 2007 Apr;83(1):86-93. doi: 10.1016/j.radonc.2007.02.011. Epub 2007 Mar 21.

Abstract

BACKGROUND AND PURPOSE

In the framework of an ESTRO ESQUIRE project, the BRAPHYQS Physics Network and the EQUAL-ESTRO laboratory have developed a procedure for checking the absorbed dose to water in the vicinity of HDR or PDR sources using a mailed TLD system. The methodology and the materials used in the procedure are based on the existing EQUAL-ESTRO external radiotherapy dose checks.

MATERIALS AND METHODS

A phantom for TLD postal dose assurance service, adapted to accept catheters from different HDR afterloaders, has been developed. The phantom consists of three PMMA tubes supporting catheters placed at 120 degrees around a central TLD holder. A study on the use of LiF powder type DTL 937 (Philitech) has been performed in order to establish the TLD calibration in dose-to-water at a given distance from (192)Ir source, as well as to determine all correction factors to convert the TLD reading into absorbed dose to water. The dosimetric audit is based on the comparison between the dose to water measured with the TL dosimeter and the dose calculated by the clinical TPS. Results of the audits are classified in four different levels depending on the ratio of the measured dose to the stated dose. The total uncertainty budget in the measurement of the absorbed dose to water using TLD near an (192)Ir HDR source, including TLD reading, correction factors and TLD calibration coefficient, is determined as 3.27% (1s).

RESULTS

To validate the procedures, the external audit was first tested among the members of the BRAPHYQS Network. Since November 2004, the test has been made available for use by all European brachytherapy centres. To date, 11 centres have participated in the checks and the results obtained are very encouraging. Nevertheless, one error detected has shown the usefulness of this audit.

CONCLUSION

A method of absorbed dose to water determination in the vicinity of an (192)Ir brachytherapy source was developed for the purpose of a mailed TL dosimetry system. The accuracy of the procedure was determined. This method allows a check of the whole dosimetry chain for this type of brachytherapy afterloading system and can easily be performed by mail to any institution in the European area and elsewhere. Such an external audit can be an efficient QC method complementary to internal quality control as it can reveal some errors which are not observable by other means.

摘要

背景与目的

在欧洲放射肿瘤学会(ESTRO)的ESQUIRE项目框架内,BRAPHYQS物理网络和EQUAL-ESTRO实验室开发了一种使用邮寄热释光剂量计(TLD)系统检查高剂量率(HDR)或脉冲剂量率(PDR)源附近水吸收剂量的程序。该程序中使用的方法和材料基于现有的EQUAL-ESTRO外照射放疗剂量检查。

材料与方法

已开发出一种适用于接受来自不同HDR后装治疗机导管的TLD邮政剂量保证服务体模。该体模由三根聚甲基丙烯酸甲酯(PMMA)管组成,这些管支撑着围绕中央TLD支架以120度放置的导管。已开展了一项关于使用DTL 937型氟化锂(LiF)粉末(Philitech公司)的研究,以确定在距铱 - 192(¹⁹²Ir)源给定距离处水吸收剂量的TLD校准,以及确定将TLD读数转换为水吸收剂量的所有校正因子。剂量学审核基于用热释光剂量计测量的水吸收剂量与临床治疗计划系统(TPS)计算的剂量之间的比较。审核结果根据测量剂量与规定剂量的比值分为四个不同级别。使用¹⁹²Ir HDR源附近的TLD测量水吸收剂量的总不确定度预算,包括TLD读数、校正因子和TLD校准系数,确定为3.27%(1s)。

结果

为验证该程序,首先在BRAPHYQS网络成员中进行了外部审核测试。自2004年11月起,该测试可供所有欧洲近距离放射治疗中心使用。迄今为止,已有11个中心参与了检查,获得的结果非常令人鼓舞。然而,检测到的一个错误表明了这种审核的有用性。

结论

为邮寄TLD剂量测定系统的目的,开发了一种在¹⁹²Ir近距离放射治疗源附近测定水吸收剂量的方法。确定了该程序的准确性。这种方法可对这类近距离放射治疗后装系统的整个剂量测定链进行检查,并且可以通过邮件轻松地在欧洲地区及其他地方的任何机构进行。这种外部审核可以作为一种有效的质量控制(QC)方法,作为内部质量控制的补充,因为它可以揭示一些用其他方法无法观察到的错误。

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