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放射治疗剂量学审核:英国临床实践与试验中三十年不断提高的标准与准确性

Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials.

作者信息

Clark Catharine H, Aird Edwin G A, Bolton Steve, Miles Elizabeth A, Nisbet Andrew, Snaith Julia A D, Thomas Russell A S, Venables Karen, Thwaites David I

机构信息

1 Department of Medical Physics, Royal Surrey County Hospital, Guildford, Surrey, UK.

2 Radiation Dosimetry Group, National Physical Laboratory, Teddington, Middlesex, UK.

出版信息

Br J Radiol. 2015;88(1055):20150251. doi: 10.1259/bjr.20150251. Epub 2015 Sep 2.

Abstract

Dosimetry audit plays an important role in the development and safety of radiotherapy. National and large scale audits are able to set, maintain and improve standards, as well as having the potential to identify issues which may cause harm to patients. They can support implementation of complex techniques and can facilitate awareness and understanding of any issues which may exist by benchmarking centres with similar equipment. This review examines the development of dosimetry audit in the UK over the past 30 years, including the involvement of the UK in international audits. A summary of audit results is given, with an overview of methodologies employed and lessons learnt. Recent and forthcoming more complex audits are considered, with a focus on future needs including the arrival of proton therapy in the UK and other advanced techniques such as four-dimensional radiotherapy delivery and verification, stereotactic radiotherapy and MR linear accelerators. The work of the main quality assurance and auditing bodies is discussed, including how they are working together to streamline audit and to ensure that all radiotherapy centres are involved. Undertaking regular external audit motivates centres to modernize and develop techniques and provides assurance, not only that radiotherapy is planned and delivered accurately but also that the patient dose delivered is as prescribed.

摘要

剂量学审核在放射治疗的发展与安全中发挥着重要作用。国家层面和大规模的审核能够设定、维持并提高标准,还具备识别可能对患者造成伤害的问题的潜力。它们能够支持复杂技术的实施,并通过对配备类似设备的中心进行基准比对,促进对可能存在的任何问题的认识与理解。本综述考察了过去30年英国剂量学审核的发展情况,包括英国参与国际审核的情况。给出了审核结果的总结,并概述了所采用的方法及吸取的经验教训。文中考虑了近期及即将开展的更复杂的审核,重点关注未来需求,包括质子治疗在英国的应用以及其他先进技术,如四维放射治疗的实施与验证、立体定向放射治疗和磁共振直线加速器。讨论了主要质量保证和审核机构的工作,包括它们如何共同努力简化审核流程,并确保所有放射治疗中心都参与其中。定期进行外部审核促使各中心实现技术现代化和发展,不仅能确保放射治疗的计划和实施准确无误,还能保证给予患者的剂量符合规定。

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