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细菌易位:机制与临床影响概述

Bacterial translocation: overview of mechanisms and clinical impact.

作者信息

Balzan Silvio, de Almeida Quadros Claudio, de Cleva Roberto, Zilberstein Bruno, Cecconello Ivan

机构信息

Postgraduate Program, Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, Sao Paulo, Brazil.

出版信息

J Gastroenterol Hepatol. 2007 Apr;22(4):464-71. doi: 10.1111/j.1440-1746.2007.04933.x.

Abstract

Bacterial translocation (BT) is a phenomenon in which live bacteria or its products cross the intestinal barrier. Gut translocation of bacteria has been shown in both animal and human studies. BT and its complications have been shown clearly to occur in animal models, but its existence and importance in humans has been difficult to ascertain. We review the mechanisms of BT and its clinical impact based on the current literature.

摘要

细菌易位(BT)是一种活菌或其产物穿过肠道屏障的现象。动物和人体研究均已证实存在细菌的肠道易位。在动物模型中已明确显示出BT及其并发症的发生,但在人类中其是否存在及其重要性却难以确定。我们根据当前文献综述了BT的机制及其临床影响。

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