人类溶质载体家族11成员1蛋白（SLC11A1）：感染、自身免疫与癌症之间的联系？
The human solute carrier family 11 member 1 protein (SLC11A1): linking infections, autoimmunity and cancer?
作者信息
Awomoyi Agnes A
机构信息
Department of Microbiology and Immunology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
出版信息
FEMS Immunol Med Microbiol. 2007 Apr;49(3):324-9. doi: 10.1111/j.1574-695X.2007.00231.x.
SLC11A1 is known to link infections, autoimmunity and cancers. A review is presented of the mechanisms by which a balance is maintained between infections caused by pathogens (viral, bacterial and protozoan; intracellular and extracellular) and disorders resulting from (acute or chronic) inflammation, and of the interactions that determine how the initial innate immune system directs subsequent acquired immune responses in human populations.
已知溶质载体家族11成员1（SLC11A1）与感染、自身免疫和癌症相关。本文综述了在由病原体（病毒、细菌和原生动物；细胞内和细胞外）引起的感染与（急性或慢性）炎症导致的病症之间维持平衡的机制，以及决定人类群体中初始固有免疫系统如何引导后续获得性免疫反应的相互作用。
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