Allen R J, Dev Borman A, Saleh G M
Essex County Hospital, Colchester, United Kingdom.
Cont Lens Anterior Eye. 2007 Dec;30(5):267-9. doi: 10.1016/j.clae.2007.02.008. Epub 2007 Mar 26.
Previous studies have investigated intraocular pressure (IOP) measurements through conventional soft (hydrogel) therapeutic contact lenses, and have found that an accurate IOP can be recorded in normal eyes, and in eyes with abnormal anterior segments. The IOP measurement through soft contact lenses may be affected by the water content and centre thickness of the lens. Silicone hydrogel contact lenses are now being used as therapeutic contact lenses due to their high oxygen permeability. The purpose of this study is to investigate if IOP can be accurately measured in a subject wearing a silicone hydrogel contact lens.
In a cohort study, the IOP was measured with a Goldmann applanation tonometer without a contact lens and then repeated with a hydrogel contact lens in situ.
The IOP of 20 eyes of 10 volunteers with no ocular pathology was measured. The mean difference (+/-S.D.) found between IOP measurement with (mean 15.55+/-1.70 mmHg) and without (mean 16.05+/-1.90 mmHg) contact lens was found to be -0.5+/-0.89 mmHg. Statistical analysis was performed which revealed a correlation coefficient of 0.89. No significant statistical difference was found between the two groups with paired t-test (p=0.19).
Accurate measurement of IOP by applanation tonometry can be achieved through a silicone hydrogel contact lens.
以往的研究通过传统的软性（水凝胶）治疗性隐形眼镜测量眼压，发现正常眼睛和前段异常的眼睛都能记录到准确的眼压。通过软性隐形眼镜测量眼压可能会受到镜片含水量和中心厚度的影响。由于硅水凝胶隐形眼镜具有高透氧性，目前正被用作治疗性隐形眼镜。本研究的目的是调查佩戴硅水凝胶隐形眼镜的受试者是否能准确测量眼压。
在一项队列研究中，先用戈德曼压平眼压计在不佩戴隐形眼镜的情况下测量眼压，然后在原位佩戴水凝胶隐形眼镜后再次测量。
对10名无眼部病变志愿者的20只眼睛进行了眼压测量。佩戴隐形眼镜（平均15.55±1.70 mmHg）和不佩戴隐形眼镜（平均16.05±1.90 mmHg）测量的眼压平均差值（±标准差）为-0.5±0.89 mmHg。进行统计分析后得出相关系数为0.89。配对t检验显示两组之间无显著统计学差异（p = 0.19）。
通过硅水凝胶隐形眼镜采用压平眼压法可以准确测量眼压。
