Holley J L, Nespor S, Rault R
Renal-Electrolyte Division, University of Pittsburgh, PA 15213.
Am J Kidney Dis. 1992 Feb;19(2):156-61. doi: 10.1016/s0272-6386(12)70125-7.
There are few data about the prevalence and characteristics of reported sleep disorders in chronic dialysis patients and, although insomnia is often used as a marker of uremia, there are few data relating complaints of sleep to adequacy of dialysis. We therefore surveyed 48 hemodialysis (HD) patients, 22 continuous peritoneal dialysis (PD) patients, and 41 healthy control subjects about disordered sleep. The questionnaire included demographic data, questions characterizing the reported sleep problems, and linear analogue scales quantitating the severity of the sleep disturbance and feelings of anxiety, worry, and sadness. Kt/V determinations were also made for each dialysis patient. Fifty-two percent of the HD, 50% of the PD, and 12% of the control subjects reported problems sleeping (P less than 0.001, all dialysis patients v controls). No differences between HD and PD in characteristics of sleep problems were seen. Sleep severity scale results confirmed sleep disorders (7.2 in those with v 0.95 in those without sleep disorders, where 0 = sleep a little problem and 10 = a big problem, P less than 0.001). Caffeine intake (P less than 0.05) and worry (P less than 0.004) were the only factors associated with reported sleep disturbances. Kt/V values (1.4 +/- 0.3) did not predict reported sleep problems. Mean reported hours of sleep per night (5.5 +/- 2 v 5.8 +/- 1.4) and desired hours of sleep per night (8.3 +/- 2 v 7.6 +/- 1.3) were similar among dialysis patients and controls reporting sleep problems. Dialysis patients and controls without self-reported sleep disorders slept a mean of 7.1 +/- 2.4 and 7 +/- 1.1 h/night, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
关于慢性透析患者中所报告的睡眠障碍的患病率及特征,相关数据较少。尽管失眠常被用作尿毒症的一个指标,但关于睡眠主诉与透析充分性之间关系的数据也很少。因此,我们对48例血液透析(HD)患者、22例持续性腹膜透析(PD)患者和41名健康对照者进行了睡眠障碍调查。问卷包括人口统计学数据、描述所报告睡眠问题的问题,以及量化睡眠障碍严重程度和焦虑、担忧及悲伤情绪的线性模拟量表。还对每位透析患者进行了Kt/V测定。52%的HD患者、50%的PD患者和12%的对照者报告存在睡眠问题(所有透析患者与对照者相比,P<0.001)。HD和PD患者在睡眠问题特征方面未见差异。睡眠严重程度量表结果证实存在睡眠障碍(有睡眠障碍者为7.2,无睡眠障碍者为0.95,其中0=睡眠稍有问题,10=严重问题,P<0.001)。咖啡因摄入量(P<0.05)和担忧情绪(P<0.004)是与所报告睡眠障碍相关的唯一因素。Kt/V值(1.4±0.3)不能预测所报告的睡眠问题。报告存在睡眠问题的透析患者和对照者每晚平均报告的睡眠时间(5.5±2对5.8±1.4)及期望的睡眠时间(8.3±2对7.6±1.3)相似。未自我报告有睡眠障碍的透析患者和对照者每晚平均睡眠时间分别为7.1±2.4小时和7±1.1小时。(摘要截短于250字)