Stallmach A, Schmidt C
Abteilung für Gastroenterologie, Hepatologie und Infektiologie, Friedrich-Schiller-Universität, Erlanger Allee 101, 07740 Jena, Germany.
Internist (Berl). 2007 Jun;48(6):606-11. doi: 10.1007/s00108-007-1835-8.
Restorative proctocolectomy with an ileal pouch-anal anastomosis is the treatment of choice in patients with ulcerative colitis (UC) and familial adenomatous polyposis requiring surgical therapy. Pouchitis is the most frequent complication, occurring in up to 50% of patients with underlying UC. Clinical symptoms of the disease are non-specific. Moreover, surgical complications must be differentiated from idiopathic pouchitis using pouchoscopy, endoscopic ultrasound or MRI of the pelvis in certain cases. The therapy for idiopathic pouchitis, its etiology and pathophysiology being unclear, is based on antibiotic treatment, usually with metronidazole or ciprofloxacin. Probiotics such as VSL#3 can be used to prevent relapse. In summary, the clinical and functional outcomes are excellent and stable for 20 years after surgery.
回肠袋肛管吻合术的修复性直肠结肠切除术是溃疡性结肠炎（UC）和需要手术治疗的家族性腺瘤性息肉病患者的首选治疗方法。袋炎是最常见的并发症，在潜在UC患者中发生率高达50%。该疾病的临床症状不具有特异性。此外，在某些情况下，必须使用袋镜检查、内镜超声或盆腔MRI将手术并发症与特发性袋炎区分开来。特发性袋炎的病因和病理生理学尚不清楚，其治疗基于抗生素治疗，通常使用甲硝唑或环丙沙星。益生菌如VSL#3可用于预防复发。总之，术后20年的临床和功能结果良好且稳定。
