Coile D C, Baker H D
Program in Psychobiology and Neuroscience, Florida State University, Tallahassee.
Vis Neurosci. 1992 Jan;8(1):27-39. doi: 10.1017/s0952523800006465.
Foveal dark adaptation in 58 subjects and photopigment regeneration in 60 subjects from 10-78 years of age exhibit parallel slowing of recovery rate with increasing age, with significant correlation of the two functions among individuals. The data are suggestive of an initial slight decline in rate before age 50, followed by a greater decline occurring at different ages in different individuals. Longitudinal data for one subject from age 40-65 show an increase in pigment regeneration time constant consistent with this idea. Foveal sensitivity and photopigment density both decrease with increasing age and are significantly correlated among individuals, although sensitivity declines more with age than does photopigment density. In contrast to earlier proposals based upon the Rushton-Dowling equation, we found no universal constant of proportionality to relate log relative threshold to photopigment within our population.
对58名受试者的中央凹暗适应以及对60名年龄在10至78岁受试者的光色素再生研究表明，随着年龄增长，恢复速率呈平行减慢趋势，且个体间这两种功能存在显著相关性。数据表明，50岁之前恢复速率最初略有下降，随后在不同个体的不同年龄出现更大幅度的下降。一名受试者从40岁到65岁的纵向数据显示，色素再生时间常数增加，这与上述观点一致。中央凹敏感度和光色素密度均随年龄增长而降低，且个体间显著相关，不过敏感度随年龄下降的幅度比光色素密度更大。与基于拉什顿 - 道林方程的早期观点不同，我们发现在我们的研究人群中，不存在将对数相对阈值与光色素相关联的通用比例常数。
