Wierink Claar D, van Diermen Denise E, Aartman Irene H A, Heymans Hugo S A
Academic Centre for Dentsitry, Amsterdam, The Netherlands.
Int J Paediatr Dent. 2007 May;17(3):163-8. doi: 10.1111/j.1365-263X.2006.00816.x.
The aim of this study was to investigate whether Dutch children with proven coeliac disease show specific dental enamel defects, and to asses whether children with the same gastrointestinal complaints, but proved no-coeliac disease, lack these specific dental enamel defects.
Eighty-one children (53 coeliac patients and 28 control subjects) were examined during the period 2003-2004 in the Oral Surgery Outpatient Clinic of the Academic Medical Centre in Amsterdam.
Twenty-nine (55%) coeliac patients had enamel defects against 5 (18%) control subjects. In the coeliac disease group, the enamel defects were diagnosed as specific in 20 (38%) children, compared with 1 (4%) in the control group. Statistical analysis showed significantly more specific enamel defects in children with coeliac disease than in children in the control group (chi(2) = 12.62, d.f. = 2, P = 0.002).
This study showed significantly more specific enamel defects in Dutch children with coeliac disease as compared with children in the control group. Dentists could play an important role in recognizing patients with coeliac disease.
本研究旨在调查确诊为乳糜泻的荷兰儿童是否存在特定的牙釉质缺陷，并评估有相同胃肠道症状但确诊无乳糜泻的儿童是否不存在这些特定的牙釉质缺陷。
2003年至2004年期间，在阿姆斯特丹学术医疗中心口腔外科门诊对81名儿童（53名乳糜泻患者和28名对照受试者）进行了检查。
29名（55%）乳糜泻患者有牙釉质缺陷，而对照受试者中有5名（18%）有牙釉质缺陷。在乳糜泻组中，20名（38%）儿童的牙釉质缺陷被诊断为特异性的，而对照组中为1名（4%）。统计分析表明，乳糜泻儿童的特异性牙釉质缺陷明显多于对照组儿童（χ² = 12.62，自由度 = 2，P = 0.002）。
本研究表明，与对照组儿童相比，荷兰乳糜泻儿童的特异性牙釉质缺陷明显更多。牙医在识别乳糜泻患者方面可发挥重要作用。
