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[乳糜泻与牙科]

[Coeliac disease and dentistry].

作者信息

van Gils T, de Boer N K H, Bouma G

出版信息

Ned Tijdschr Tandheelkd. 2015 Sep;122(9):443-8. doi: 10.5177/ntvt.2015.09.15145.

Abstract

Coeliac disease is a chronic autoimmune enteropathy, which is caused by exposure to dietary gluten in genetically pre-disposed individuals. -Approximately 0.5-1% of the Dutch population has coeliac disease, diag-nosed at both younger and older age. Treatment consists of a strict gluten-free diet. Symptoms can be diverse, including dental and oral manifestations. These dental and oral manifestations are often seen in patients with coeliac disease, although most of them are nonspecific. This is not the case for the symmetric enamel defects described by Aine and colleagues, which are very specific for coeliac disease. Early diagnosing of coeliac disease is important to prevent complications by (vitamin) deficiencies or rare (pre) malignant forms of coeliac disease. There seems to be a role for dentists in early diagnosing of coeliac disease.

摘要

乳糜泻是一种慢性自身免疫性肠病,由遗传易感性个体摄入膳食麸质引起。荷兰约0.5%-1%的人口患有乳糜泻,在年轻人和老年人中均可诊断。治疗方法是严格的无麸质饮食。症状可能多种多样,包括牙齿和口腔表现。这些牙齿和口腔表现常在乳糜泻患者中出现,尽管大多数是非特异性的。但Aine及其同事描述的对称性釉质缺陷并非如此,它们对乳糜泻具有高度特异性。早期诊断乳糜泻对于预防因(维生素)缺乏或罕见的(癌前)乳糜泻恶性形式导致的并发症很重要。牙医在乳糜泻的早期诊断中似乎可以发挥作用。

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