细针采样技术评估。
An assessment of fine-needle sampling techniques.
作者信息
Titoria Puneet, Siva Thiru M, Malik Tass
机构信息
Department of Otolaryngology, Torbay Hospital, Torquay, UK.
出版信息
Ann R Coll Surg Engl. 2010 Jul;92(5):429-31. doi: 10.1308/rcsann.2010.92.5.429. Epub 2010 May 19.
INTRODUCTION
Fine-needle cytology sampling, when adequate, is highly sensitive and specific for tissue-type diagnosis, with figures of 94% and 88%, respectively. This study explores the technique of sampling to reduce interoperator variability and ensure maximal tissue yield.
MATERIALS AND METHODS
Apple cortical tissue was sampled as a proxy of human lymph node. A total of 200 samples, by four methods, with 50 by each sampling method, were taken using blue venepuncture needles and weighed to assess tissue yield.
RESULTS
Results were analysed using one-way analysis of variance and Tukey's HSD test. Comparable yields, by mass, were achieved by both straight lance and coring techniques (P > 0.05). Significantly greater yield was achieved with a multiplanar technique (P < 0.05).
CONCLUSIONS
Multiplanar sampling increases mass yield of tissue in fine-needle sampling. Coring appears to have little bearing on yield.
引言
细针细胞学采样在样本充足时，对组织类型诊断具有高度敏感性和特异性，其敏感性和特异性分别为94%和88%。本研究探索了采样技术，以减少操作者间的差异并确保获得最大量的组织样本。
材料与方法
采用苹果皮质组织作为人类淋巴结的替代物。使用蓝色静脉穿刺针通过四种方法共采集200个样本，每种采样方法采集50个样本，并对样本进行称重以评估组织样本量。
结果
采用单因素方差分析和Tukey's HSD检验对结果进行分析。直刺法和钻取法所获得的组织样本质量相当（P>0.05）。多平面采样法获得的样本量显著更大（P<0.05）。
结论
在细针采样中，多平面采样可增加组织样本量。钻取法似乎对样本量影响不大。
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