纤维肌性发育异常可能预示着颈动脉夹层出现症状复发。
Fibromuscular dysplasia may herald symptomatic recurrence of cervical artery dissection.
作者信息
de Bray J M, Marc G, Pautot V, Vielle B, Pasco A, Lhoste P, Dubas F
机构信息
Department of Neurology, University Hospital Angers, Angers, France.
出版信息
Cerebrovasc Dis. 2007;23(5-6):448-52. doi: 10.1159/000101470. Epub 2007 Apr 2.
BACKGROUND
The prevalence of fibromuscular dysplasia (FMD) in patients with cervical artery dissection (CAD) is unknown. Our objectives were to assess the risk of CAD recurring as a stroke or a transient ischemic attack and the association of these events with FMD.
METHODS
We prospectively included and followed 103 consecutive patients who had been admitted for a CAD. The median follow-up was 4 years (range 4 months to 10 years). The main criteria for inclusion were a mural hematoma demonstrated by cervical magnetic resonance imaging and/or signs suggesting CAD on 2 other investigations. FMD was diagnosed on the so-called string of beads pattern by digital subtraction angiography.
RESULTS
Five patients had CAD recurrence (60% occurred late). Four of these 5 patients had FMD. In 4 patients, CAD recurrence involved another cervical artery.
CONCLUSION
The rate of symptomatic CAD recurrence was 1% per year and was often related to FMD.
背景
纤维肌性发育异常（FMD）在颈动脉夹层（CAD）患者中的患病率尚不清楚。我们的目标是评估CAD复发为中风或短暂性脑缺血发作的风险，以及这些事件与FMD的关联。
方法
我们前瞻性纳入并随访了103例因CAD入院的连续患者。中位随访时间为4年（范围4个月至10年）。纳入的主要标准是颈椎磁共振成像显示的壁内血肿和/或其他两项检查提示CAD的体征。通过数字减影血管造影在所谓的串珠样模式下诊断FMD。
结果
5例患者出现CAD复发（60%为晚期复发）。这5例患者中有4例患有FMD。在4例患者中，CAD复发累及另一根颈动脉。
结论
有症状的CAD复发率为每年1%，且通常与FMD有关。
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