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石榴汁可能是抗白塞病药物库中的一种潜在补充：一种假说。

Pomegranate juice may be a potential addition to anti-Behçet armamentarium: a hypothesis.

作者信息

Borhani Haghighi Afshin, Bagheri Mansooreh

机构信息

Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Clin Rheumatol. 2007 Oct;26(10):1709-10. doi: 10.1007/s10067-007-0608-z. Epub 2007 Apr 4.

DOI:10.1007/s10067-007-0608-z
PMID:17406934
Abstract

Behçet's disease (BD) is a systemic vasculitis. We speculate that local or systemic administration of the pomegranate juice may be useful in the treatment of BD. Immunomodulatory, antioxidants and antibacterial characteristics of pomegranate juice may rationalize this hypothesis.

摘要

白塞病（BD）是一种全身性血管炎。我们推测，局部或全身给予石榴汁可能对白塞病的治疗有用。石榴汁的免疫调节、抗氧化和抗菌特性可能使这一假设具有合理性。

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本文引用的文献

1
The association between total antioxidant status and oxidative stress in Behçet's disease.白塞病中总抗氧化状态与氧化应激之间的关联。
Rheumatol Int. 2006 Sep;26(11):1005-9. doi: 10.1007/s00296-006-0126-3. Epub 2006 May 20.
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Pomegranate juice sugar fraction reduces macrophage oxidative state, whereas white grape juice sugar fraction increases it.石榴汁糖分部分可降低巨噬细胞的氧化状态，而白葡萄汁糖分部分则会使其升高。
Atherosclerosis. 2006 Sep;188(1):68-76. doi: 10.1016/j.atherosclerosis.2005.10.027. Epub 2005 Dec 5.
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Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress.
石榴汁对氧化敏感基因及受扰切应力部位内皮型一氧化氮合酶活性的有益作用。
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Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury.在新生儿缺氧缺血性脑损伤动物模型中，母体饮食补充石榴汁具有神经保护作用。
Pediatr Res. 2005 Jun;57(6):858-64. doi: 10.1203/01.PDR.0000157722.07810.15. Epub 2005 Mar 17.
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Pomegranate extract inhibits Staphylococcus aureus growth and subsequent enterotoxin production.石榴提取物可抑制金黄色葡萄球菌的生长及随后的肠毒素产生。
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Antiviral activities of medicinal herbs traditionally used in southern mainland China.中国内地南方传统使用的草药的抗病毒活性。
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7
Efficacy, safety, and pharmacokinetics of multiple administration of infliximab in Behçet's disease with refractory uveoretinitis.英夫利昔单抗多次给药治疗难治性葡萄膜视网膜炎型白塞病的疗效、安全性及药代动力学
J Rheumatol. 2004 Jul;31(7):1362-8.
8
Pathogenesis of Adamantiades-Behçet's disease.白塞病的发病机制
Med Microbiol Immunol. 2003 Aug;192(3):149-55. doi: 10.1007/s00430-002-0167-5. Epub 2003 Mar 5.
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Immunomodulatory proanthocyanidins from Ecdysanthera utilis.来自红背菜的免疫调节原花青素。
J Nat Prod. 2002 Apr;65(4):505-8. doi: 10.1021/np010414l.
10
Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin.石榴果实提取物及其花青素（矢车菊素、花青素和天竺葵素）的抗氧化活性。
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