神经生长因子对大鼠颈上神经节中环磷酸腺苷水平的影响。
The effect of nerve growth factor on cycle AMP levels in superior cerival ganglia of the rat.
作者信息
Nikodijevic B, Nikodijevic O, Yu M Y, Pollard H, Guroff G
出版信息
Proc Natl Acad Sci U S A. 1975 Dec;72(12):4769-71. doi: 10.1073/pnas.72.12.4769.
Abstract
Nerve growth factor (NGF) produces a several-fold increase in the cyclic AMP concentration in rat superior cervical ganglia in organ culture within 5 min. An increase can be seen with as little as 40 ng/ml of NGF. Oxidized NGF is without effect. The increase in the cAMP concentration produced by NGF is prevented by the addition of antiserum to NGF.
摘要
神经生长因子（NGF）可在5分钟内使器官培养的大鼠颈上神经节中的环磷酸腺苷（cAMP）浓度增加数倍。低至40 ng/ml的NGF即可产生这种增加。氧化型NGF则无此作用。添加NGF抗血清可阻止NGF所引起的cAMP浓度升高。
相似文献
1
The effect of nerve growth factor on cycle AMP levels in superior cerival ganglia of the rat.
Proc Natl Acad Sci U S A. 1975 Dec;72(12):4769-71. doi: 10.1073/pnas.72.12.4769.
2
Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor.
J Biol Chem. 1980 Nov 10;255(21):10481-92.
3
Is there a second messenger for nerve growth factor-induced phosphatidylinositol turnover in rat superior cervical ganglia?
Brain Res. 1978 Nov 17;157(1):173-7. doi: 10.1016/0006-8993(78)91009-0.
4
Mutually independent cyclic AMP and sodium responses to nerve growth factor in embryonic chick dorsal root ganglia.
J Neurochem. 1981 Jul;37(1):222-8. doi: 10.1111/j.1471-4159.1981.tb05312.x.
5
Effects of nerve growth factor on cyclic AMP levels in embryonic chick dorsal root ganglia following factor deprivation.
J Neurochem. 1979 Jun;32(6):1845-51. doi: 10.1111/j.1471-4159.1979.tb02299.x.
6
Nerve growth factor-mediated induction of tyrosine hydroxylase in rat superior cervical ganglia in vitro.
J Biol Chem. 1978 Nov 25;253(22):8013-5.
7
Nerve growth factor: relationship to the cyclic AMP system of sensory ganglia.
Science. 1973 Oct 5;182(4107):79-81. doi: 10.1126/science.182.4107.79.
8
Effects of nerve growth factor and nerve growth factor antiserum on tyrosine hydroxylase and dihydropterine reductase activities in rat superior cervical ganglia in vivo.
J Neurochem. 1977 Apr;28(4):851-2. doi: 10.1111/j.1471-4159.1977.tb10637.x.
9
Nerve growth factor stimulates the development of substance P in sensory ganglia.
Proc Natl Acad Sci U S A. 1980 Jan;77(1):649-52. doi: 10.1073/pnas.77.1.649.
10
cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor.
Proc Natl Acad Sci U S A. 1988 Feb;85(4):1257-61. doi: 10.1073/pnas.85.4.1257.
引用本文的文献
1
Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.
J Cell Biol. 1986 Sep;103(3):887-93. doi: 10.1083/jcb.103.3.887.
2
Intraventricular administration of nerve growth factor induces ornithine decarboxylase in peripheral tissues of the rat.
Proc Natl Acad Sci U S A. 1978 May;75(5):2512-5. doi: 10.1073/pnas.75.5.2512.
3
Nerve growth factor increases activity of ornithine decarboxylase in superior cervical ganglia of young rats.
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4681-4. doi: 10.1073/pnas.74.10.4681.
4
Growth regulation by nerve growth factor.
Mol Cell Biochem. 1979 Dec 14;28(1-3):67-91. doi: 10.1007/BF00223360.
5
Control of adenylate cyclase from secretory vesicle membranes by beta-adrenergic agents and nerve growth factor.
Proc Natl Acad Sci U S A. 1976 Mar;73(3):771-4. doi: 10.1073/pnas.73.3.771.
本文引用的文献
1
METABOLIC ASPECTS OF THE EFFECT OF NERVE GROWTH FACTOR ON SYMPATHETIC AND SENSORY GANGLIA: PROTEIN AND RIBONUCLEIC ACID SYNTHESIS.
Biochim Biophys Acta. 1965 Jan 11;95:111-20. doi: 10.1016/0005-2787(65)90216-9.
2
Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitro.
Dev Biol. 1963 Mar;6:653-9. doi: 10.1016/0012-1606(63)90149-0.
3
Metabolic effects of a specific nerve growth factor (NGF) on sensory and sympathetic ganglia: enhancement of lipid biosynthesis.
J Neurochem. 1965 Aug;12(8):705-8. doi: 10.1111/j.1471-4159.1965.tb06784.x.
4
Glucose metabolism in embryonic ganglia: effect of nerve growth factor [NGF] and insulin.
Brain Res. 1968 Mar;7(3):452-4. doi: 10.1016/0006-8993(68)90011-5.
5
Tissue culture assay of nerve growth factor and of the specific antiserum.
Exp Cell Res. 1970 Mar;59(3):383-92. doi: 10.1016/0014-4827(70)90645-2.
6
The nerve growth factor: its mode of action on sensory and sympathetic nerve cells.
Harvey Lect. 1966;60:217-59.
7
Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia.
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1598-602. doi: 10.1073/pnas.68.7.1598.
8
The role of nerve growth factor in the ramification of sympathetic nerve fibres into the rat iris in organ culture.
J Neurochem. 1972 Sep;19(9):2025-9. doi: 10.1111/j.1471-4159.1972.tb05112.x.
9
Nerve growth factor and insulin.
Science. 1972 May 5;176(4034):482-8. doi: 10.1126/science.176.4034.482.
10
The role of the tryptophan residues in the activity of the nerve growth factor.
Biochim Biophys Acta. 1970 Sep 29;214(3):478-82. doi: 10.1016/0005-2795(70)90307-7.
Zotero 插件