Degenhardt Louisa, Roxburgh Amanda, McKetin Rebecca
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.
Med J Aust. 2007 Apr 2;186(7):342-5. doi: 10.5694/j.1326-5377.2007.tb00933.x.
To examine trends in hospital separations related to "drug-induced" psychosis for cannabis and methamphetamine, in the context of patterns of cannabis and methamphetamine use in the Australian population.
Analysis of prospectively collected data from the National Hospital Morbidity Database on hospital separations primarily attributed to drug-induced psychosis (July 1993 - June 2004), and specifically for cannabis and amphetamines (1999-2004). Calculation of Australian population-adjusted rates of drug-induced psychosis hospital separations using estimated resident population data from the Australian Bureau of Statistics (at 30 June each year) and data on cannabis and methamphetamine use from the 2004 National Drug Strategy Household Survey.
Number of hospital separations due to drug-induced psychosis, and standardised (age-specific) rates per million population and per million users.
There have been notable increases in hospital separations due to drug-induced psychosis, which appear to have been driven by amphetamine-related rather than cannabis-related episodes. The rate of hospital separations was higher for amphetamine users than for cannabis users in all age groups, and the rate increased among older amphetamine users.
The risk of hospitalisation for a drug-induced psychotic episode associated with amphetamine use appears to be greater than that for cannabis use in all age groups.
在澳大利亚人群大麻和甲基苯丙胺使用模式的背景下,研究与大麻和甲基苯丙胺“药物所致”精神病相关的住院情况趋势。
对国家医院发病率数据库前瞻性收集的数据进行分析,这些数据主要归因于药物所致精神病(1993年7月 - 2004年6月),特别是针对大麻和苯丙胺(1999 - 2004年)。使用澳大利亚统计局(每年6月30日)的估计常住人口数据以及2004年国家药物战略家庭调查中关于大麻和甲基苯丙胺使用的数据,计算澳大利亚人口调整后的药物所致精神病住院率。
药物所致精神病的住院人数,以及每百万人口和每百万使用者的标准化(按年龄组)率。
药物所致精神病的住院人数显著增加,这似乎是由与苯丙胺相关而非与大麻相关的发作所致。在所有年龄组中,苯丙胺使用者的住院率高于大麻使用者,并且老年苯丙胺使用者的住院率有所上升。
在所有年龄组中,与使用苯丙胺相关的药物所致精神病发作的住院风险似乎大于使用大麻的风险。