Marks David J, Miller Scott R, Schulz Kurt P, Newcorn Jeffrey H, Halperin Jeffrey M
Division of Child and Adolescent Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.
Psychiatry Res. 2007 Jun 30;151(3):221-30. doi: 10.1016/j.psychres.2006.07.010. Epub 2007 Apr 3.
Childhood aggression has both biological and environmental underpinnings. However, the manner in which these factors interact to influence various types of aggression remains an important area of study. The current study examined the degree to which biological risk and psychosocial adversity, both alone and in combination, are associated with childhood aggression. Linear regression procedures were used to assess the extent to which biological risk status (low vs. high serotonergic responsivity, as measured by prolactin response to fenfluramine), magnitude of psychosocial risk, and the interaction of these factors predicted parent and teacher ratings of aggression and delinquency. After accounting for the independent contribution of biological and psychosocial risk, the interaction of biological and psychosocial risk was significantly associated with parent-rated aggression and marginally related to parent-rated delinquency. In contrast, no such interaction was observed for teacher-rated aggression. Findings suggest that individuals at biological risk for aggression may be particularly vulnerable to the impact of psychosocial adversity.
儿童期攻击行为具有生物学和环境基础。然而，这些因素相互作用以影响各种类型攻击行为的方式仍是一个重要的研究领域。当前的研究考察了生物学风险和心理社会逆境单独以及共同作用时与儿童期攻击行为相关的程度。采用线性回归程序来评估生物学风险状态（通过氟苯丙胺刺激后催乳素反应测量的低血清素反应性与高血清素反应性）、心理社会风险程度以及这些因素的相互作用对家长和教师评定的攻击行为和犯罪行为的预测程度。在考虑了生物学和心理社会风险的独立作用后，生物学和心理社会风险的相互作用与家长评定的攻击行为显著相关，与家长评定的犯罪行为存在微弱关联。相比之下，在教师评定的攻击行为中未观察到这种相互作用。研究结果表明，具有攻击行为生物学风险的个体可能特别容易受到心理社会逆境的影响。
