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与哺乳动物C型RNA病毒p30蛋白相关的抗原位于人类系统性红斑狼疮的肾小球中。

Antigen related to mammalian type-C RNA viral p30 proteins is located in renal glomeruli in human systemic lupus erythematosus.

作者信息

Mellors R C, Mellors J W

出版信息

Proc Natl Acad Sci U S A. 1976 Jan;73(1):233-7. doi: 10.1073/pnas.73.1.233.

DOI:10.1073/pnas.73.1.233
PMID:174099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC335875/
Abstract

An antigen related to mammalian type-C RNA viral p30 proteins was shown by the use of anti-p30 sera and the indirect immunofluorescence method to be present in the kidneys and spleen in a fulminant fatal case of human systemic lupus erythematosus and to be located in the glomeruli, the site of active lupus diffuse glomerulonephritis.

摘要

通过使用抗p30血清和间接免疫荧光法，发现在一例暴发性致命的人类系统性红斑狼疮病例的肾脏和脾脏中存在一种与哺乳动物C型RNA病毒p30蛋白相关的抗原，且该抗原位于肾小球，即活动性狼疮弥漫性肾小球肾炎的病变部位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce3/335875/1f62a423d483/pnas00670-0241-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce3/335875/dd8880d9d688/pnas00670-0241-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce3/335875/1f62a423d483/pnas00670-0241-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce3/335875/dd8880d9d688/pnas00670-0241-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce3/335875/1f62a423d483/pnas00670-0241-b.jpg

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