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2型单纯疱疹病毒与急性无菌性脑膜炎。脑脊液中分离出单纯疱疹病毒的病例的临床特征。

Herpes simplex virus type 2 and acute aseptic meningitis. Clinical features of cases with isolation of herpes simplex virus from cerebrospinal fluids.

作者信息

Sköldenberg B, Jeansson S, Wolontis S

出版信息

Scand J Infect Dis. 1975;7(4):227-32. doi: 10.3109/inf.1975.7.issue-4.01.

DOI:10.3109/inf.1975.7.issue-4.01
PMID:174191
Abstract

Herpes simplex virus (HSV) was recovered from the cerebrospinal fluids (CSF) of 10 patients with acute aseptic meningitis. HSV type 1 was isolated from the CSF of a 6-month-old boy. The other 9 HSV isolates from CSF were from adults in the age-group 15 to 29 years; 7 of these isolates were available for typing and were identified as HSV type 2. In a further 9 patients with acute aseptic meningitis and belonging to the same age-group a HSV infection was suggested by a significant titre rise in complement-fixing antibodies against HSV. The clinical features of the 10 patients with HSV isolation from CSF are presented. The 6-month-old boy with HSV type 1 had an acute benign aseptic meningitis. Seven of the 9 adults with HSV isolation from CSF (type 2 in all isolates available for typing) had an acute uncomplicated aseptic meningitis, one patient (with type 2 isolated) had an acute meningoencephalitis and one (isolate untyped) an acute meningomyelitis.

摘要

从10例急性无菌性脑膜炎患者的脑脊液中分离出单纯疱疹病毒(HSV)。从一名6个月大男婴的脑脊液中分离出1型单纯疱疹病毒。另外9份从脑脊液中分离出的HSV毒株来自15至29岁的成年人;其中7份毒株可用于分型,被鉴定为2型单纯疱疹病毒。在另外9例属于同一年龄组的急性无菌性脑膜炎患者中,抗HSV补体结合抗体效价显著升高提示存在HSV感染。本文介绍了10例从脑脊液中分离出HSV患者的临床特征。感染1型HSV的6个月大男婴患急性良性无菌性脑膜炎。9例从脑脊液中分离出HSV的成年人中(所有可用于分型的毒株均为2型),7例患急性无并发症无菌性脑膜炎,1例患者(分离出2型毒株)患急性脑膜脑炎,1例(毒株未分型)患急性脊髓膜炎。

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