Ryan J J
Can Vet J. 1983 Mar;24(3):72-5.
Young pigs raised on a pentachlorophenol-treated wooden floor showed a high mortality. The deaths ceased when the original treated wood was covered with untreated plywood. Analysis of the wood, mother's milk, and young pig tissues was carried out for pentachlorophenol and chlorinated dibenzo-p-dioxins. Pentachlorophenol was found in the wood and mother's milk but not in the young pig tissues. Concentrations of the higher chlorinated dioxins were found in the wood at the ppm level, in the mother's milk at the low ppt level and in the skin and liver of the young pigs at the ppb level. A comparison of the concentrations of hexa-and hepta-dioxin isomers in the wood, and in the piglet skin and liver indicated that a selective absorption and/or metabolism of these isomers had occurred. The results of this case history implicate the higher chlorinated dioxins in the mortality of the young pigs and underline the danger of using technical pentachlorophenol for wood treatment in association with food producing animals.
在经过五氯苯酚处理的木地板上饲养的幼猪死亡率很高。当原来经过处理的木材被未处理的胶合板覆盖后，死亡情况停止。对木材、母乳和幼猪组织进行了五氯苯酚和氯代二苯并 - 对 - 二恶英的分析。在木材和母乳中发现了五氯苯酚，但在幼猪组织中未发现。在木材中发现高氯代二恶英的浓度为百万分之一级别，在母乳中为万亿分之一的低级别，在幼猪的皮肤和肝脏中为十亿分之一级别。木材中六氯和七氯二恶英异构体的浓度与仔猪皮肤和肝脏中的浓度比较表明，这些异构体发生了选择性吸收和/或代谢。这个案例的结果表明高氯代二恶英与幼猪的死亡率有关，并强调了将工业用五氯苯酚用于木材处理以及与食用动物相关联时的危险性。
