Marrie T J
Can Vet J. 1990 Aug;31(8):555-63.
Q or "query" fever is a zoonosis caused by the organism Coxiella burnetii. Cattle, sheep and goats are the most common reservoirs of this organism. The placenta of infected animals contains high numbers (up to 10(9)/g) of C. burnetii. Aerosols occur at the time of parturition and man becomes infected following inhalation of the microorganism. The spectrum of illness in man is wide and consists of acute and chronic forms. Acute Q fever is most often a self-limited flu-like illness but may include pneumonia, hepatitis, or meningoencephalitis. Chronic Q fever almost always means endocarditis and rarely osteomyelitis. Chronic Q fever is not known to occur in animals other than man. An increased abortion and stillbirth rate are seen in infected domestic ungulates.Four provinces (Nova Scotia, New Brunswick, Ontario and Alberta) reported cases of Q fever in 1989.A vaccine for Q fever has recently been licensed in Australia.
Q热或“疑问”热是由伯氏考克斯体引起的一种人畜共患病。牛、绵羊和山羊是该病原体最常见的宿主。受感染动物的胎盘含有大量(高达每克10⁹个)伯氏考克斯体。分娩时会产生气溶胶,人吸入该微生物后会被感染。人类的疾病谱很广,包括急性和慢性形式。急性Q热通常是一种自限性的流感样疾病,但可能包括肺炎、肝炎或脑膜脑炎。慢性Q热几乎总是意味着心内膜炎,很少是骨髓炎。除人类外,慢性Q热在其他动物中未见发生。受感染的家养有蹄类动物的流产和死产率会增加。1989年,四个省份(新斯科舍省、新不伦瑞克省、安大略省和艾伯塔省)报告了Q热病例。最近,一种Q热疫苗在澳大利亚获得了许可。