Hansen Peter Riis
Gentofte Hospital, Kardiologisk Laboratorium, Hellerup.
Ugeskr Laeger. 2007 Mar 26;169(13):1209-11.
Stress induced "Takotsubo" cardiomyopathy is a recently described cardiovascular syndrome mimicking acute myocardial infarction and characterised by reversible left ventricular dysfunction with apical ballooning in patients without coronary artery disease. It usually affects elderly women and is preceded by emotional or physical stress. With early diagnosis and aggressive therapy, the prognosis is favourable. The syndrome is probably underdiagnosed, and the pathophysiology may involve coronary vascular dysfunction, excessive sympathetic stimulation and left ventricular outflow obstruction.
应激性“章鱼壶”心肌病是一种最近描述的心血管综合征,酷似急性心肌梗死,其特征为无冠状动脉疾病的患者出现可逆性左心室功能障碍伴心尖部气球样变。它通常影响老年女性,且发病前有情绪或身体应激。早期诊断并积极治疗,预后良好。该综合征可能诊断不足,其病理生理学可能涉及冠状动脉血管功能障碍、过度交感神经刺激和左心室流出道梗阻。