Hawkins Kevin, Wang Sara, Rupnow Marcia F T
Thomson Medstat, Cambridge, MA 02140, USA.
J Occup Environ Med. 2007 Apr;49(4):368-74. doi: 10.1097/JOM.0b013e31803b9510.
The purpose of this study was to determine the indirect cost burden associated with migraine.
Data were obtained from Thomson-Medstat's Health and Productivity Management (HPM) database for the 2002 through 2003 calendar years. The migraine cohort was composed of patients who had a diagnosis of migraine or migraine-specific abortive prescription medication, or both. A control cohort of patients without migraine was matched to patients in the migraine cohort. The average annual indirect burden of illness (BOI) of migraine and a national indirect BOI were estimated.
Annual indirect expenditures were significantly higher in the migraine group compared with the control group ($4453 vs $1619; P<0.001). The national annual indirect BOI, excluding presenteeism, was estimated to be $12 billion (mostly attributed to absenteeism).
Migraine imparts a substantial indirect cost burden. Projected to a national level, this amounts to an annual cost to US employers of approximately $12 billion.
本研究旨在确定与偏头痛相关的间接成本负担。
数据取自汤姆森 - 美思医疗（Thomson-Medstat）2002年至2003年历年的健康与生产力管理（HPM）数据库。偏头痛队列由诊断为偏头痛或使用偏头痛特异性终止性处方药或两者皆有的患者组成。将无偏头痛患者的对照队列与偏头痛队列中的患者进行匹配。估算偏头痛的年均间接疾病负担（BOI）和全国间接BOI。
偏头痛组的年度间接支出显著高于对照组（4453美元对1619美元；P<0.001）。全国年度间接BOI（不包括出勤主义成本）估计为120亿美元（主要归因于旷工）。
偏头痛带来了巨大的间接成本负担。推算至全国范围，这相当于美国雇主每年约120亿美元的成本。
