Kabat G C, Hebert J R
Division of Epidemiology, American Health Foundation, New York, New York 10017.
Cancer Res. 1991 Dec 15;51(24):6510-3.
Black males have higher age-adjusted lung cancer incidence rates compared to white males, and blacks of both sexes have higher rates of increase in lung cancer incidence over past decades. The majority of black smokers smoke mentholated cigarettes. These observations prompted us to assess the effect of smoking mentholated cigarettes on lung cancer risk, using data from a hospital-based case-control study of tobacco-related cancers. Analysis was restricted to current cigarette smokers and was carried out on 588 male lung cancer cases and 914 male control patients and on 456 female lung cancer cases and 410 female controls interviewed between 1985 and 1990. The prevalence of menthol usage did not differ between cases and controls of either sex. No significant association was observed between either short-term (1-14 years) or long-term (15+ years) menthol use and lung cancer in logistic regression analyses adjusting for covariates. For specific histological types of lung cancer there was no indication of an association with menthol usage.
与白人男性相比,黑人男性经年龄调整后的肺癌发病率更高,并且在过去几十年中,两性黑人的肺癌发病率上升速度更快。大多数黑人吸烟者吸薄荷醇香烟。这些观察结果促使我们利用一项基于医院的烟草相关癌症病例对照研究的数据,评估吸薄荷醇香烟对肺癌风险的影响。分析仅限于当前吸烟者,对1985年至1990年间访谈的588例男性肺癌病例、914例男性对照患者、456例女性肺癌病例和410例女性对照进行了分析。薄荷醇使用的流行率在两性的病例和对照之间没有差异。在对协变量进行调整的逻辑回归分析中,短期(1 - 14年)或长期(15年以上)使用薄荷醇与肺癌之间均未观察到显著关联。对于特定组织学类型的肺癌,没有迹象表明与薄荷醇使用有关联。