Lee Jung Hoon, Kim Tae Nyeun, Choi Sun Taek, Jang Byung Ik, Shin Kyeong-Cheol, Lee Sam Beom, Shim Young Ran
Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Korean J Intern Med. 2007 Mar;22(1):24-7. doi: 10.3904/kjim.2007.22.1.24.
Behçet's disease (BD) is a chronic relapsing multisystem disease characterized by oral ulceration, genital ulceration and ocular lesions. Gastrointestinal involvement is rare, often difficult to treat and associated with a high mortality rate. We treated a 47-year-old Korean man with BD who had a recurrent intestinal ulcer with tumor necrosis factor alpha antibody (infliximab); he initially underwent right hemicolectomy due to uncontrolled intestinal bleeding. For patients with intestinal BD who fail to respond to conventional treatment, infliximab may be a safe and effective new therapeutic option.
白塞病（BD）是一种慢性复发性多系统疾病，其特征为口腔溃疡、生殖器溃疡和眼部病变。胃肠道受累较为罕见，治疗往往困难，且死亡率高。我们治疗了一名47岁的韩国白塞病男性患者，该患者有复发性肠道溃疡，使用肿瘤坏死因子α抗体（英夫利昔单抗）进行治疗；他最初因肠道出血无法控制而接受了右半结肠切除术。对于常规治疗无效的肠道白塞病患者，英夫利昔单抗可能是一种安全有效的新治疗选择。
