使用BD phoenix系统评估莫拉西林检测凝固酶阴性葡萄球菌中甲氧西林耐药性的情况。
Evaluation of moxalactam with the BD phoenix system for detection of methicillin resistance in coagulase-negative staphylococci.
作者信息
Pupin H, Renaudin H, Join-Lambert O, Bébéar C, Mégraud F, Lehours P
机构信息
CHU de Bordeaux, Hôpital Pellegrin, Laboratoire de Bactériologie, Place Amélie Raba Léon, 33076 Bordeaux, France.
出版信息
J Clin Microbiol. 2007 Jun;45(6):2005-8. doi: 10.1128/JCM.00578-07. Epub 2007 Apr 11.
Abstract
The performance of moxalactam with the BD Phoenix system for the detection of methicillin resistance in coagulase-negative staphylococci was evaluated by use of a collection of 186 strains. Moxalactam was a better drug as an indicator of methicillin resistance for mecA-positive strains than oxacillin and cefoxitin were. For strains other than Staphylococcus saprophyticus, a moxalactam MIC >16 microg/ml was indicative of methicillin resistance.
摘要
使用BD Phoenix系统，通过对186株菌株的检测，评估了莫西拉酸检测凝固酶阴性葡萄球菌中耐甲氧西林情况的性能。对于mecA阳性菌株，莫西拉酸作为耐甲氧西林的指示药物比苯唑西林和头孢西丁更好。对于腐生葡萄球菌以外的菌株，莫西拉酸的最低抑菌浓度（MIC）>16微克/毫升表明耐甲氧西林。
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