Yamamoto Hidekazu, Deshmukh Nayneeta, Gourevitch David, Taniere Phillipe, Wallace Michael, Cullen Michael H
Department of Urology, Queen Elizabeth Hospital, University Hospital Birmingham NHS Trust, Birmingham, UK.
Int J Urol. 2007 Mar;14(3):261-3. doi: 10.1111/j.1442-2042.2007.01685.x.
A rare case of a gastric presentation of a seminoma with burned out primary testicular tumor is described. The patient initially presented with upper gastrointestinal hemorrhage. Endoscopic biopsies were suggestive of seminoma, and testicular ultrasound revealed a focal lesion and testicular microcalcification. Treatment consisted of bilateral orchidectomy, followed by four cycles of etoposide and bleomycin, where a complete response was achieved. Testicular histology was consistent with the "burned out" phenomenon and no tumor cells were found. There are only two previously reported cases of extragonadal seminoma in the stomach.
本文描述了一例罕见的胃原发性睾丸肿瘤消退后精原细胞瘤的病例。患者最初表现为上消化道出血。内镜活检提示为精原细胞瘤，睾丸超声显示有局灶性病变和睾丸微钙化。治疗包括双侧睾丸切除术，随后进行四个周期的依托泊苷和博来霉素治疗，达到了完全缓解。睾丸组织学与“消退”现象相符，未发现肿瘤细胞。此前仅有两例胃内性腺外精原细胞瘤的报道。
