Liu Chao, Wang Hong-qing, Li Bao-ming, Chen Ruo-yun
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.
Zhongguo Zhong Yao Za Zhi. 2007 Feb;32(3):235-7.
To study the chemical constituents from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang.
To isolated the compounds by silica gel and sephadex LH -20 column chromatography and their structures were elucidate by means of spectral analysis.
Six sterols, one fatty acid and one of diketopiperazines were obtained from CHCl3 fraction of EtOH extract and identified as ergosta-7, 22-dien-3beta-ol (1), ergosterol (2), 6, 9-epidioxyergosta-7, 22-dien-3beta-ol (3), 5, 8-epidioxiergosta-6, 22-dien-3beta-ol (4), ergosta-7, 22-dien-3-one (5), beta-sitosterol (6), alpha-Hydroxytetracosanoic acid (7), cyclo (D-Pro-D-Val) (8).
Componds 1-8 are isolated from G. sinense Zhao, Xu et Zhang for the first time.
研究紫芝子实体的化学成分。
采用硅胶柱色谱和葡聚糖凝胶LH -20柱色谱分离化合物，并通过光谱分析确定其结构。
从乙醇提取物的氯仿部位得到6个甾醇、1个脂肪酸和1个二酮哌嗪，分别鉴定为麦角甾-7,22-二烯-3β-醇（1）、麦角甾醇（2）、6,9-环氧麦角甾-7,22-二烯-3β-醇（3）、5,8-环氧麦角甾-6,22-二烯-3β-醇（4）、麦角甾-7,22-二烯-3-酮（5）、β-谷甾醇（6）、α-羟基二十四烷酸（7）、环（D-脯氨酸-D-缬氨酸）（8）。
化合物1 - 8首次从紫芝中分离得到。
