Duclos Philippe, Okwo-Bele Jean-Marie
Immunization, Vaccines and Biologicals, World Health Organization, 20, avenue Appia, CH-1211 Geneva 27, Suisse.
Med Sci (Paris). 2007 Apr;23(4):409-16. doi: 10.1051/medsci/2007234409.
The World Health Organization (WHO) has a dual mandate of providing global policies, standards and norms as well as support for member countries in applying such policies and standards to national programmes with the aim to improve health. The vaccine world is changing and with it the demands and expectations of the global and national policy makers, donors, and other interested parties. Changes pertain to : new vaccines and technologies developments, vaccine safety issues, regulation and approval of vaccines, and increased funding flowing through new financing mechanisms. This places a special responsibility on WHO to respond effectively. WHO has recently reviewed and optimized its policy making structure for vaccines and immunization and adjusted it to the new Global Immunization Vision and Strategy, which broadens the scope of immunization efforts to all age groups and vaccines with emphasis on integration of immunization delivery with other health interventions. This includes an extended consultation process to promptly generate evidence base recommendations, ensuring transparency of the decision making process and added communication efforts. This article presents the objectives and impact of the process set to develop global immunization policies, norms, standards and recommendations. The key advisory committees landscape contributing to this process is described. This includes the Strategic Advisory Group of Experts, the Global Advisory Committee on Vaccine Safety and the Expert Committee on Biological Standardization. The elaboration of WHO vaccine position papers is also described.
世界卫生组织(WHO)肩负双重使命,既要提供全球政策、标准和规范,又要支持成员国将这些政策和标准应用于国家项目,以改善健康状况。疫苗领域正在发生变化,全球和国家政策制定者、捐助者及其他相关方的需求和期望也随之改变。这些变化涉及:新疫苗和技术的发展、疫苗安全问题、疫苗的监管与审批,以及通过新融资机制流入的资金增加。这使得世卫组织肩负起有效应对的特殊责任。世卫组织最近对其疫苗和免疫政策制定结构进行了审查和优化,并根据新的《全球免疫远景与战略》进行了调整,该战略将免疫工作的范围扩大到所有年龄组和各类疫苗,重点是将免疫接种与其他卫生干预措施相结合。这包括一个延长的协商过程,以便迅速产生有证据支持的建议,确保决策过程的透明度,并加大宣传力度。本文介绍了制定全球免疫政策、规范、标准和建议的过程的目标和影响。描述了促成这一过程的主要咨询委员会的情况。这包括战略咨询专家组、全球疫苗安全咨询委员会和生物标准化专家委员会。还介绍了世卫组织疫苗立场文件的拟订情况。