Yamamoto Kazuhiko, Irie Masahiro, Sakamoto Yoko, Ohmori Susumu, Yoshinari Mototaka
Institute of Health Science, Kyushu University, and Kyushu Central Hospital, Fukuoka, Japan.
J Physiol Anthropol. 2007 Mar;26(2):149-58. doi: 10.2114/jpa2.26.149.
The aim of this study was to examine the relationship between the stress score measured using the Inventory to Measure Psychosocial Stress (IMPS) and biomedical parameters regarding health status among apparently healthy subjects in order to evaluate the validity of the IMPS. Out of the 1,941 public school workers in Kyushu and Okinawa, Japan, who were admitted to a hospital for medical check-ups, 1,499 workers responded to questionnaires which assessed the degree of stress response (i.e., stress score) measured using the IMPS, and the degree of stress tolerance capacity (i.e., stress intolerance score) measured using the Inventory to Measure Stress Tolerance Capacity (IMST). One thousand two-hundred and one workers (684 men and 517 women) were analyzed, excluding 298 subjects who were taking medication for hypertension, hyperuricemia, hyperlipidemia and diabetes, or had a value for glycosylated hemoglobin (HbA1c)>or=6.0 percent. An increase in the stress score was positively associated with an increase in both body fat percentage and glycosylated hemoglobin values among men, while it was positively associated with an increase in plasma triglyceride concentrations among women. The stress score significantly correlated with the value for glycosylated hemoglobin even after controlling for age, body mass index, alcohol consumption, smoking, and exercise among men. An increase in the stress intolerance score was positively associated with an increase in body fat percentage among men, while it was positively associated with an increase in body weight, body mass index, and body fat percentage among women. Our result that the stress score measured using the IMPS was associated with obesity and unfavorable glycemic changes is in congruency with the model that psychosocial stress has a detrimental effect on humans by inducing obesity and insulin resistance, suggesting that the IMPS is a valid means to evaluate psychosocial stress levels among an otherwise healthy population.
本研究旨在探讨使用心理社会压力量表（IMPS）测量的压力得分与明显健康受试者健康状况的生物医学参数之间的关系，以评估IMPS的有效性。在日本九州和冲绳的1941名公立学校工作人员中，他们因体检入院，1499名工作人员回答了问卷，问卷评估了使用IMPS测量的压力反应程度（即压力得分），以及使用压力耐受能力量表（IMST）测量的压力耐受能力程度（即压力不耐受得分）。分析了1201名工作人员（684名男性和517名女性），排除了298名正在服用高血压、高尿酸血症、高脂血症和糖尿病药物，或糖化血红蛋白（HbA1c）值≥6.0%的受试者。压力得分的增加与男性体脂百分比和糖化血红蛋白值的增加呈正相关，而与女性血浆甘油三酯浓度的增加呈正相关。即使在控制了男性的年龄、体重指数、饮酒、吸烟和运动后，压力得分仍与糖化血红蛋白值显著相关。压力不耐受得分的增加与男性体脂百分比的增加呈正相关，而与女性体重、体重指数和体脂百分比的增加呈正相关。我们的结果表明，使用IMPS测量的压力得分与肥胖和不利的血糖变化有关，这与心理社会压力通过诱导肥胖和胰岛素抵抗对人类产生有害影响的模型一致，表明IMPS是评估健康人群中心理社会压力水平的有效手段。
