De Marinis M, Stocchi F, Testa S R, De Pandis F, Agnoli A
Department of Neurological Sciences, La Sapienza University, Rome, Italy.
Funct Neurol. 1991 Jul-Sep;6(3):279-83.
Sweating and superficial vasodilator responses were studied in 22 patients suffering from Parkinson's disease in order to evaluate the thermoregulatory function. Sweating was evaluated on different areas of the body with a colorimetric method (Minor's method). The superficial vasodilatation at the level of the face was assessed after oral intake of nitroglycerin by means of telethermography. Sweating and superficial vasodilatation were reduced in parkinsonian patients compared with control subjects. Asymmetries in sweating and superficial vasodilator responses were also observed between the left and right sides of the body in the patients. The decreased heat elimination was more apparent on the symptomatic side in patients with hemiparkinsonism. No relationship was found between the alterations of the thermoregulation and the other clinical features of Parkinson's disease.
为评估体温调节功能，对22例帕金森病患者的出汗及体表血管舒张反应进行了研究。采用比色法（Minor法）评估身体不同部位的出汗情况。口服硝酸甘油后，通过远红外热成像法评估面部的体表血管舒张情况。与对照组相比，帕金森病患者的出汗及体表血管舒张功能降低。患者身体左右两侧的出汗及体表血管舒张反应也存在不对称性。在偏侧帕金森病患者中，有症状一侧的散热减少更为明显。未发现体温调节改变与帕金森病的其他临床特征之间存在关联。
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