Rao Narsing A
Doheny Eye Institute, 1450 San Pablo Street, DVRC 211, Los Angeles, CA 90033, USA.
Int Ophthalmol. 2007 Apr-Jun;27(2-3):81-5. doi: 10.1007/s10792-006-9029-2. Epub 2007 Apr 14.
Typical histopathologic features of Vogt-Koyanagi-Harada disease (VKH) include granulomatous panuveitis with preservation of the choriocapillaris and exudative retinal detachment. In the chronic stage of the disease, however, histologic changes consist of nongranulomatous uveitis followed, in the chronic recurrent stage, by granulomatous uveitis and involvement of the choriocapillaris. In chronic VKH the peripheral fundus scars are not Dalén-Fuchs nodules; they are, instead, indicative of focal chorioretinal atrophy with loss of retinal pigment epithelium.
伏格特-小柳-原田病（VKH）典型的组织病理学特征包括肉芽肿性全葡萄膜炎伴脉络膜毛细血管保留及渗出性视网膜脱离。然而，在疾病的慢性期，组织学改变为非肉芽肿性葡萄膜炎，在慢性复发期则为肉芽肿性葡萄膜炎并累及脉络膜毛细血管。在慢性VKH中，周边眼底瘢痕并非达伦-富克斯结节；相反，它们提示局灶性脉络膜视网膜萎缩伴视网膜色素上皮缺失。
