Erba Stefano, Govetto Andrea, Scialdone Antonio, Casalino Giuseppe
Oftalmico Hospital, ASST Fatebenefratelli Sacco, Milano, Italy.
GMS Ophthalmol Cases. 2021 Mar 12;11:Doc06. doi: 10.3205/oc000179. eCollection 2021.
Vogt-Koyanagi-Harada disease (VKH) is an autoimmune severe multisystem condition characterized by both ocular and systemic findings that should be promptly recognized and treated. Although invasive imaging modalities, namely fluorescein angiography and indocyanine green angiography, are still the gold standard for the diagnosis and follow-up of the ocular findings in VKH, the role of retinal non-invasive imaging including optical coherence tomography angiography (OCTA) is under investigation and is not mentioned in the current diagnostic criteria of VKH. The aim of this manuscript was to report the clinical course and the multimodal retinal imaging of a VKH case and to discuss the role of OCTA in this condition. Our case supports the evidence that OCTA is able to help determine disease activity and progression in VKH. We therefore contend that OCTA should be considered for future developing diagnostic criteria of this condition.
伏格特-小柳-原田病（VKH）是一种自身免疫性严重多系统疾病，其特征为眼部和全身表现，应及时识别并治疗。尽管侵入性成像方式，即荧光素血管造影和吲哚菁绿血管造影，仍是VKH眼部表现诊断和随访的金标准，但包括光学相干断层扫描血管造影（OCTA）在内的视网膜非侵入性成像的作用正在研究中，且目前VKH的诊断标准中未提及。本文的目的是报告1例VKH病例的临床病程和多模式视网膜成像，并讨论OCTA在这种疾病中的作用。我们的病例支持了OCTA能够帮助确定VKH疾病活动和进展的证据。因此，我们认为在未来制定这种疾病的诊断标准时应考虑OCTA。
