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梅毒亚种雅司螺旋体（帕里阿曼菌株）感染的超微结构特征。

Ultrastructural aspects of infection with Treponema pallidum subspecies pertenue (Pariaman strain).

作者信息

Engelkens H J, Vuzevski V D, ten Kate F J, van der Heul P, van der Sluis J J, Stolz E

机构信息

Department of Dermatology and Venereology, University Hospital Rotterdam-Dijkzigt, The Netherlands.

出版信息

Genitourin Med. 1991 Oct;67(5):403-7. doi: 10.1136/sti.67.5.403.

DOI:10.1136/sti.67.5.403
PMID:1743714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1194741/
Abstract

OBJECTIVE

To study ultrastructural aspects of infection with Treponema pertenue (Pariaman strain), originating from West Sumatra, Indonesia.

MATERIALS AND METHODS

Biopsy material originating from skin lesions in ten young children suffering from early infectious yaws in Indonesia, and rabbit testicular tissue inoculated with T pertenue. Human skin as well as rabbit testicular tissue was examined by means of conventional electron microscopy.

RESULTS

In human skin, treponemes were found in interepidermal spaces in 5 out of 10 specimens. In two of five positive specimens, treponemes were also seen in the dermis. In one out of five specimens from rabbit testicular tissue a profusion of treponemes was found lying in the interstitial myxomatous tissue. Microorganisms showed no adhesion to fibroblasts.

CONCLUSION

This ultrastructural study of T pertenue demonstrated the scarcity and focal distribution of treponemes in tissue and did not reveal any morphological differences from the Gauthier strain of T pertenue. No differences from the ultrastructure of T pallidum were observed either.

摘要

目的

研究源自印度尼西亚西苏门答腊的品他密螺旋体（帕里阿曼菌株）感染的超微结构特征。

材料与方法

取自印度尼西亚10名患有早期感染性雅司病的幼儿皮肤病变的活检材料，以及接种了品他密螺旋体的兔睾丸组织。采用传统电子显微镜检查人皮肤和兔睾丸组织。

结果

在人皮肤中，10个标本中有5个在表皮间隙发现了密螺旋体。在5个阳性标本中的2个中，真皮中也可见密螺旋体。在兔睾丸组织的5个标本中的1个中，在间质黏液瘤样组织中发现大量密螺旋体。微生物未显示与成纤维细胞的黏附。

结论

本品他密螺旋体的超微结构研究表明，密螺旋体在组织中的数量稀少且呈局灶性分布，与品他密螺旋体的高蒂埃菌株在形态上没有差异。也未观察到与梅毒螺旋体超微结构的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/ceded834cfa5/genitmed00041-0050-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/3727478999ac/genitmed00041-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/5e5aaef4fb9c/genitmed00041-0048-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/eab4eae2e260/genitmed00041-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/1a51ca6944b8/genitmed00041-0049-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/c617154c3181/genitmed00041-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/ceded834cfa5/genitmed00041-0050-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/3727478999ac/genitmed00041-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/5e5aaef4fb9c/genitmed00041-0048-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/eab4eae2e260/genitmed00041-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/1a51ca6944b8/genitmed00041-0049-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/c617154c3181/genitmed00041-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a951/1194741/ceded834cfa5/genitmed00041-0050-b.jpg

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Electronmicrography of treponemas from cases of yaws, pinta, and the so-called Cuban form of pinta.
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Treponema pallidum in early syphilitic lesions in humans during high-dosage penicillin therapy. An electron microscopical study.大剂量青霉素治疗期间人类早期梅毒病变中的梅毒螺旋体。一项电子显微镜研究。
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