Fazio Giovanni, Corrado Giovanni, Zachara Elisabetta, Rapezzi Carlo, Sulafa Ali K, Sutera Loredana, Pizzuto Caterina, Stollberger Claudia, Sormani Luca, Finsterer Joseph, Benatar Abraham, Di Gesaro Gabriele, Cascio Caterina, Cangemi Debora, Cavusoglu Yuksel, Baumhakel Magnus, Drago Fabrizio, Carerj Scipione, Pipitone Salvatore, Novo Salvatore
Division of Cardiology, Casa del Sole Hospital, Palermo, Italy.
Pacing Clin Electrophysiol. 2007 Apr;30(4):544-6. doi: 10.1111/j.1540-8159.2007.00706.x.
Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for ventricular arrhythmias is unclear. Some reports have found that the fatal ventricular arrhythmias may occur in approximately half of the patients. In this report we investigated about this association.
In total we evaluated a continuous series of 238 patients affected by non-compaction. Periodic Holter monitoring was performed every 6 months for 4 years. Only 11 patients had documented ventricular tachycardia, which was sustained in two cases and non-sustained in nine. In no cases we observed ventricular fibrillation.
Non-compaction alone does not seem to be a risk factor for malignant ventricular arrhythmias.
孤立性左心室心肌致密化不全是心肌形态发生不完全的结果，导致胚胎心肌持续存在。这种情况通过左心室过度突出的小梁网和小梁间深隐窝得以识别。这些小梁间隐窝是否是室性心律失常的有利基质尚不清楚。一些报告发现，约一半的患者可能发生致命性室性心律失常。在本报告中，我们对这种关联进行了研究。
我们总共评估了连续的238例心肌致密化不全患者。每6个月进行一次为期4年的定期动态心电图监测。只有11例患者记录到室性心动过速，其中2例为持续性，9例为非持续性。未观察到心室颤动病例。
单纯的心肌致密化不全似乎不是恶性室性心律失常的危险因素。
