Gennari Luigi, Bilezikian John P
College of Physicians and Surgeons, 630 W. 168th Street, New York, NY 10032, USA.
Curr Rheumatol Rep. 2007 Apr;9(1):71-7. doi: 10.1007/s11926-007-0025-y.
Osteoporosis has long been long considered a disease of the aging female skeleton. However, it is now clear that men are also at risk for this disorder. Epidemiologic studies have confirmed that osteoporotic fractures in men are an increasing public health problem, in part due to increased longevity and increased public awareness. Recent large-scale population studies in men have led to advances in our understanding of bone fragility and its treatment in men. This article reviews what is known about the factors in men that lead to acquisition, maintenance, and loss of bone, as well as new insights into causes, pathogenesis, and treatment of osteoporosis in men.
长期以来，骨质疏松症一直被视为一种老年女性骨骼疾病。然而，现在很明显男性也有患这种疾病的风险。流行病学研究证实，男性骨质疏松性骨折是一个日益严重的公共卫生问题，部分原因是寿命延长和公众意识提高。最近针对男性的大规模人群研究推动了我们对男性骨脆性及其治疗的认识。本文综述了已知的导致男性骨质获得、维持和流失的因素，以及对男性骨质疏松症病因、发病机制和治疗的新见解。
