Gennari Luigi, Bilezikian John P
Department of Internal Medicine, Endocrine-Metabolic Sciences and Biochemistry, University of Siena, Siena 53100, Italy.
Endocrinol Metab Clin North Am. 2007 Jun;36(2):399-419. doi: 10.1016/j.ecl.2007.03.008.
Osteoporosis has long been considered to be a disease of the aging female skeleton. As awareness of the pervasiveness of this disorder increases, it is clear that men are also at risk for this disorder. Recent epidemiological studies have confirmed that osteoporosis in men is an increasing health problem. This development not only has its roots in increased longevity but also in increased awareness of this problem in men. The purpose of this article is to review what is known about the factors in men that lead to acquisition, maintenance, and loss of bone, as well as new insights about the causes, pathogenesis, and treatment of osteoporosis in men.
长期以来，骨质疏松症一直被认为是老年女性骨骼的疾病。随着对这种疾病普遍性的认识不断提高，很明显男性也有患这种疾病的风险。最近的流行病学研究证实，男性骨质疏松症是一个日益严重的健康问题。这种情况的出现不仅源于寿命的延长，也源于男性对这个问题的认识提高。本文的目的是回顾关于男性导致骨质获取、维持和流失的因素的已知情况，以及关于男性骨质疏松症的病因、发病机制和治疗的新见解。
