Chaudhuri S, Varshney J P
Clinical Diagnosis laboratory, Referral Veterinary Polyclinic, Indian Veterinary Research Institute, Izatnagar 243122 UP, India.
Homeopathy. 2007 Apr;96(2):90-4. doi: 10.1016/j.homp.2007.02.010.
Homeopathic Crotalus horridus 200C was evaluated in 13 clinical cases of babesiosis in dogs, compared with another 20 clinical cases treated with diminazine. Babesiosis is an important tropical tick-borne haemoprotozoan disease in dogs clinically manifested by anorexia, dehydration, temperature, dullness/depression, diarrhoea/constipation, pale mucosa, hepatomegaly, vomiting/nausea, splenomegaly, distended abdomen/ascites, yellow coloured urine, emaciation/weight loss, and occular discharge. The diagnosis of babesiosis was based on cytological evidence of Babesia gibsoni in freshly prepared blood smears. The dogs were treated with oral C. horridus 200C, 4 pills four times daily for 14 days (n=13) or diminazine aceturate 5 mg/kg single intramuscularly dose (n=20). All the dogs were administered 5% Dextrose normal saline at 60 ml/kg intravenously for 4 days. Initial clinical scores were similar in both groups and showed similar progressive improvement with the two treatments over 14 days. Parasitaemia also improved in both groups, but haematological values showed no change. No untoward reactions were observed. It appears that C. horridus is as effective in causing clinical recovery in moderate cases of canine babesiosis caused by Babesia gibsoni as the standard drug diminazine. Large scale randomized trials are indicated for more conclusive results.
顺势疗法的糙皮响尾蛇200C在13例犬巴贝斯虫病临床病例中进行了评估，并与另外20例接受地美硝唑治疗的临床病例进行了比较。巴贝斯虫病是犬类一种重要的热带蜱传播血液原虫病，临床表现为厌食、脱水、体温异常、精神沉郁/抑郁、腹泻/便秘、黏膜苍白、肝肿大、呕吐/恶心、脾肿大、腹部膨隆/腹水、尿液发黄、消瘦/体重减轻和眼部分泌物。巴贝斯虫病的诊断基于新鲜制备血涂片中巴贝斯吉氏虫的细胞学证据。犬只接受口服糙皮响尾蛇200C治疗，每日4次，每次4丸，持续14天（n = 13），或接受乙酰地美硝唑5 mg/kg单次肌肉注射剂量治疗（n = 二十）。所有犬只均静脉注射5%葡萄糖生理盐水，剂量为60 ml/kg，持续4天。两组的初始临床评分相似，并且在14天的两种治疗过程中均显示出相似的逐步改善。两组的寄生虫血症也有所改善，但血液学值没有变化。未观察到不良反应。看来糙皮响尾蛇在由巴贝斯吉氏虫引起的犬巴贝斯虫病中度病例中，在促使临床康复方面与标准药物地美硝唑一样有效。需要进行大规模随机试验以获得更确凿的结果。
