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[新生儿先天性口咽肿瘤:团队诊断与治疗中的问题]

[Congenital oropharyngeal tumors in the newborn: problems in team diagnosis and treatment].

作者信息

Barbuţa O I, Aprodu G S, Gavrilescu Simona, Mihaila Doina, Iliev Gh, Olaru V, Munteanu V, Savu Anca

机构信息

Facultatea de Medicina, Universitatea de Medicina şi Farmacie "Gr.T. Popa", Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2006 Oct-Dec;110(4):883-6.

Abstract

There are a great variety of lesions of oral cavity which may require surgical intervention in neonatal period. The differential diagnoses include tumors (malignant, teratoma, cystic hygroma, lymphangioma, hemangioma), congenital epulis, dermoid cysts, ranula. Congenital epulis of the newborn is a rare tumour which is usually benign. Epulis is also known as a congenital gingival granular cell tumour because of its histological features. Female babies are affected 8-10 times more often than males. Epulis is located on the maxillary ridge twice as often as on the mandible, mostly as single tumours but rarely as multiple tumours. The histogenesis of the tumour is unknown. Spontaneous regression of congenital epulis has been reported in a few cases. However, surgical excision is generally indicated due to interference with feeding or respiration. Recurrence of the tumour after surgery has not been reported yet. We report two cases of congenital epulis, one in 2 hour female neonate and one in a 7 days male neonate. In spite of the rarity of this pathology, the interval between presentation in this two cases was ten days. In one case it was an antenatal diagnosis by ultrasonography, in the other it was associated a genital anomalies (hypospadias). The treatment was surgical excision. The intra- and postoperative course was uneventful.

摘要

口腔有各种各样的病变,在新生儿期可能需要手术干预。鉴别诊断包括肿瘤(恶性、畸胎瘤、囊状水瘤、淋巴管瘤、血管瘤)、先天性牙龈瘤、皮样囊肿、舌下囊肿。新生儿先天性牙龈瘤是一种罕见的肿瘤,通常为良性。由于其组织学特征,牙龈瘤也被称为先天性牙龈颗粒细胞瘤。女婴受影响的几率比男婴高8至10倍。牙龈瘤位于上颌嵴的情况是位于下颌骨的两倍,大多为单个肿瘤,但很少为多个肿瘤。该肿瘤的组织发生尚不清楚。少数病例报告了先天性牙龈瘤的自发消退。然而,由于影响喂养或呼吸,通常需要手术切除。尚未有术后肿瘤复发的报告。我们报告两例先天性牙龈瘤病例,一例为2小时大的女新生儿,另一例为7天大的男新生儿。尽管这种病理情况罕见,但这两例病例的就诊间隔为10天。一例通过超声进行了产前诊断,另一例伴有生殖器异常(尿道下裂)。治疗方法为手术切除。术中及术后过程均顺利。

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