Kaimbo Wa Kaimbo D, Parys-Van Ginderdeuren R, Missotten L
Department of Ophthalmology, University of Kinshasa, D R Congo.
Bull Soc Belge Ophtalmol. 1998;268:135-41.
To determine the clinical characteristics of conjunctival squamous cell carcinoma and conjunctival intraepithelial neoplasia in AIDS patients.
A review of AIDS patients with biopsy-confirmed conjunctival squamous cell carcinoma and conjunctival intraepithelial neoplasia seen between 1994 and 1997.
Ten patients, aged from 25 to 46 years (average, 37.3 years) were seen. There were three men and seven women. The mean delay of diagnosis was 7 months. Of the 10 patients, three had squamous cell carcinoma of the conjunctiva and seven had conjunctival intraepithelial neoplasia. Both eyes were involved with equal frequency. Lesions involved the corneoscleral limbus and the conjunctiva in eight patients and the conjunctiva in two patients. Localization of lesions was temporal in six patients, nasal in three patients and inferior in one patient. All patients were treated by excision of the lesions. A recurrence was seen in two patients (during the follow-up of 6 months).
The conjunctival squamous cell carcinoma and intraepithelial neoplasia in AIDS patients in this study showed similar clinical characteristics as those reported in immunocompetent persons, but occurred in a younger age group and were more aggressive.
确定艾滋病患者结膜鳞状细胞癌和结膜上皮内瘤变的临床特征。
回顾1994年至1997年间经活检确诊为结膜鳞状细胞癌和结膜上皮内瘤变的艾滋病患者。
共观察到10例患者，年龄在25至46岁之间（平均37.3岁）。其中男性3例，女性7例。平均诊断延迟时间为7个月。10例患者中，3例患有结膜鳞状细胞癌，7例患有结膜上皮内瘤变。双眼受累频率相同。8例患者的病变累及角膜缘和结膜，2例患者仅累及结膜。病变位于颞侧的有6例，鼻侧的有3例，下方的有1例。所有患者均接受了病变切除术。2例患者出现复发（随访6个月期间）。
本研究中艾滋病患者的结膜鳞状细胞癌和上皮内瘤变表现出与免疫功能正常者报告的相似临床特征，但发病年龄较轻且侵袭性更强。
