Tipton Janelle M, McDaniel Roxanne W, Barbour Laurel, Johnston Mary Pat, Kayne Marilyn, LeRoy Patricia, Ripple Marita L
University of Toledo Medical Center, Ohio, USA.
Clin J Oncol Nurs. 2007 Feb;11(1):69-78. doi: 10.1188/07.CJON.69-78.
Chemotherapy-induced nausea and vomiting (CINV) continues to have a considerable effect on the physical and psychological well-being of patients with cancer, despite significant advances in antiemetic drugs since the 1990s. This article reviews and summarizes past and current empirical evidence related to interventions for CINV. A resource that summarizes evidence-based interventions for CINV is critical for effective management of this distressing symptom. Pharmacologic and nonpharmacologic interventions are appraised. Finally, gaps in the literature and opportunities for research, education, and practice changes are discussed.
尽管自20世纪90年代以来止吐药物取得了重大进展,但化疗引起的恶心和呕吐(CINV)仍然对癌症患者的身心健康产生相当大的影响。本文回顾并总结了过去和当前与CINV干预措施相关的实证证据。一份总结CINV循证干预措施的资源对于有效管理这种令人痛苦的症状至关重要。对药物和非药物干预措施进行了评估。最后,讨论了文献中的空白以及研究、教育和实践变革的机会。